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IDYOPATIK MEMBRANOZ NEFROPATI TEDAVİSİNDE PREDNİZOLON VE SİKLOFOSFAMİD KOMBİNASYONUNUN ETKİNLİĞİ

EFFECTIVENESS OF PREDNISOLONE AND CYCLOPHOSPHAMIDE COMBINATION IN IDIOPATHIC MEMBRANOUS NEPHROPATHY

Journal Name:

  • Türk Nefroloji, Diyaliz ve Transplantasyon Dergisi

Publication Year:

  • 1998

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
Twenty-two adults with the nephrotic syndrome related to idiopathic membranous nephropathy were assigned to conservative treatment or prednisolone and cyclophosphamide combination. At the end of follow up (median: 5,6 months) 15 of 18 treated patients were in complete or partial remission, as compared with 1 of 4 conservative treatment group. Thirteen of treated patients were in complete remission as compared with none of the conservative treatment group. We conclude that prednisolone and cyclophosphamide for short time favors remission of the nephrotic syndrome in adults with idiopathic membranous nephropathy.
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Abstract (Original Language): 
Idyopatik membranöz nefropatiye bağlı nefrotik sendromu olan 22 erişkin hastaya prednizolon-siklofosfamid kombinasyonu ve konservatif tedavi uygulandı. Ortalama 5.6 aylık izlem süresinin sonunda immünosüpresif tedavi gören gruptaki 18 hastadan 15 i komplet veyaparsiyel remisyona girerken konservatif tedavi grubunda 4 hastadan 1 tanesi remisyona girmişti. İmmunsupressif tedavi grubunda 13 hasta tam remisyona girerken konservatif tedavi gurubunda tam remisyona giren hasta yoktu. Biz idiopatik membranöz nefropatiye bağlı nefrotik sendromu olan erişkin hastalarda remisyonun sağlanmasında kısa süreli prednizolon-siklofosfamid tedavisinin yararlı olduğu sonucunu çıkarttık.
FULL TEXT (PDF): 
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  • 1
24-27
  • Turkish

REFERENCES

References: 

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