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DİYALİZE HASTALARDA KEMIK YOĞUNLUĞUNUN TIBIAL ULTRASONOGRAFIK DEĞERLENDIRILMESI

TIBIAL ULTRASOUND EVALUATION OF BONE DENSITY IN DIALYZED PATIENTS

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Abstract (2. Language): 
End stage renal disease (ESRD) patients are at risk of having low bone density (BD) due to disease related and general risk factors. This study was to designed to assess the cortical BD and risk factors, by tibial ultrasound evaluation, in dialysis patients. We included 40 ESRD patients and 37 healthy subjects with matched properties for osteopenia. Tibial ultrasound velocity (TUV) and t score were investigated by Soundscan 2000 device. ESRD patients had lower TUV and t score than control subjects(p=0.001). BD did not change between hemodialysis and continuous ambulatory peritoneal dialysis patients. Serum iPTH levels and dialysis duration negatively correlated with SOS and t scores. No such correlation was found out for age, BMI and heparin exposure. Cortical BD lessens and quality deteriorates increasing probability of fractures in cortical bone in dialysed patients.
Abstract (Original Language): 
Son dönem böbrek yetmezi iMi hastalar(SDBY), hastalığa bağlı ve genel faktörlerin etkisi ile düşük kemik yoğunluğuna (KY) sahip olma riski taşırlar. Bu çalışmada diyaliz hastalarında kortikal KY, tibial ultrasonografik yöntemle değerlendirildi ve ostec neni risk faktörleri araştırıldı. Çalışmaya 40 SDBYli vz 37 sağlıklı kontrol alındı. İki grup genel risk faktörleri açısından homojendi. Tibial ses hızı (SH) ve t skoru Soundscan 2000 cihazı ile değerlendirildi. Bu değerler SDSY'li hastalarda anlamlı olarak düşük bulundu(p=0.001). Hemodializ ve devamlı ayaktan periton diyalizi hastaları arasında SH ve t skoru açısından fark bulunamadı. Serum iPTH ve diyaliz süresi ile bu parametreler arasında negatif korelasyon saptanırken; yaş, vücut kitle indeksi ve heparin kullanımı ile korelasyon saptanmadı. Diyaliz hastalarında kortikal KY ve kemik kalitesi düşüktür, olası kırık riski fazladır.
FULL TEXT (PDF): 
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