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ERİTROSİT MEMBRAN SERTLİĞİ (VEYA) ERİTROSİT DEFORMABİLİTESİ; PROTEİNÜRİK HASTALARDA KAN VE PLAZMA VİSKOZİTELERİ

ERYTHROCYTE MEMBRANE STIFFNESS (OR) RED CELL DEFORMABILITY, BLOOD AND PLASMA VISCOSITY IN PROTEINURIC PATIENTS

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Abstract (2. Language): 
In recent years, anemia in nephrotic syndrome has been the subject of investigation. In addition to erythropoietin deficiency the anemia of proteinuric patients is tried to be explained by a shortened erythrocyte lifespan due to decreased red deformability. Twelve proteinuric patients were compared with two age and sex-matched control groups (anemic and healthy). Red cell deformability and viscosities at three different shear rates were evaluated. It is demonstrated that in proteinuric patients red cell deformability and blood viscosities at different shear rates were decreased.
Abstract (Original Language): 
Son yıllarda nefrotik sendromlu hastalardaki anemi irdelenmeye başlanmıştır. Erythropoietin eksikliği dışında proteinürik hastalardaki anemi eritrosit deformabilitesi bozulması nedeniyle kısalmış eritrosit yaşam süresi ile açıklanmaya çalışılmıştır. On iki proteinürik hasta yaş ve cins ile uyumlu iki kontrol grubu ile karşüaştırılmıştır (anemik ve sağlıklı). Eritrosit deformabilitesi ve değişik kayma hızlarında kan ve plazma viskoziteleri değerlendirildi. Hafif ve orta dereceli renal yetersizlikte proteinürinin tek başına eritrosit deformabilitesini ve değişik kayma hızlarında kan vizkositelerini azalttığı gösterilmiştir
FULL TEXT (PDF): 
206-212

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