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Sigara Bırakmada Farmakoterapi

PHARMACOTHERAPY IN SMOKING CESSATION

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Abstract (2. Language): 
Smoking behavior is maintained by nicotine, which is thought to be the principal cause of addiction. The fact that many people die due to smoking related disorders or cancer increases the atten¬tion to smoking cessation programs and pharmacotherapy. However, other alternative strategies need to be developed because of low success rates of nicotine replacement therapy used widely for smoking cessation. Understanding the underlying neurophysiologic and pharmacological reasons of tobacco dependence are important for the development of new methods for helping smoking cessation. While tobacco use is decreasing in the developed countries, it is increasing in the developing coun¬tries. Because of this reason, multiple and different pharmaco¬logical treatment are in use.
Abstract (Original Language): 
Sigara içme davranışı, nikotinin neden olduğu düşünülen bağımlılık nedeniyle devam ettirilmektedir. Birçok insanın, sigara içimine bağlı hastalıklar ya da kanser nedeniyle ölmesi, gün geçtikçe sigara bırakma programları ve farmakoterapisine ilgiyi artırmaktadır. Özellikle sigara bırakmada yaygın olarak kullanılan nikotin replasmanından beklenen faydanın görülememiş olması, alternatif tedavi stratejilerinin geliştirilmesi ihtiyacını doğurmuştur. Sigara bırakmada yardımcı olacak birçok yeni yöntem, bağımlılığın altında yatan nörofizyolojik ve farmakolojik nedenlerin anlaşılması ile gelişmektedir. Sigara içme oranı gelişmekte olan ülkelerde artmakta iken, gelişmiş ülkelerde azalmaktadır. Tüm bu nedenlerle sigara bırakma programlarında birden çok ve çeşitli tedavilerin kul¬lanılması gündemdedir.
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