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Gestasyonel diyabetes mellitusta serum magnezyum düzeyleri

Serum magnesium levels in gestational diabetes

Journal Name:

Publication Year:

DOI: 
doi:10.2399/tahd.10.064
Abstract (2. Language): 
Objective: To assess the relation between gestational diabetes and daily magnesium intake and magnesium deficiency in preg¬nant women with gestational diabetes. Methods: Fifty-three patients pre-diagnosed as gestational diabetes and 49 healthy pregnant women who were examined at the Endocrinology and Obstetric Outpatiet Clinics from April 2008 to January 2009 were included in the study. Body mass index (BMI) of patients were determined, obstetric characteristic, histo¬ry of diabetes in the family was investigated and symptoms of magnesium deficiency were assessed. American Food and Nutrition Board's references were used to assess the nutrition sta¬tus of patients. HbA1c, serum magnesium and calcium, kidney and liver function tests, amylase levels were measured and com¬plete urine analysis was performed. Data were tested by correla¬tion and multiple linear regression analysis. Results: Mean age, gravida, parity and body mass index were sig¬nificantly higher in patient group (p<0.05). The ratio of women who had a body mass index higher than 30 before pregnancy in the gestational diabetes group was 30.2%, and the ratio of those of whose BMI was between 25-29.9 was 50.9%. No significant differences were found between groups in terms of daily magne¬sium intake and serum magnesium levels (p=0.234, p=0.337, respectively). Daily magnesium intake was significantly higher in patients with nausea and vomiting (p=0.001, p=0.006). No significant difference was found between serum magnesium levels and HbA1c and serum calcium levels (p=0.444, p=0.614, respectively). Conclusions: Although slight decreases were seen in serum mag¬nesium levels during pregnancy, no differences were found in this study either in daily magnesium intake or serum magnesium lev¬els between pregnant women with gestational diabetes and with¬out gestational diabetes.
Abstract (Original Language): 
Amaç: Beslenme ile alınan günlük ortalama magnezyum miktarı ve magnezyum eksikliği ile gestasyonel diyabet arasındaki ilişkiyi araştırmak. Yöntem: Çalışma, Nisan 2008 - Ocak 2009 tarihleri arasında, gebe ve endokrinoloji polikliniklerinde gestasyonel diyabet tanısı alan 53 hasta ile 49 sağlıklı gebe üzerinde yürütüldü. Gebelerin beden kitle indeksi (BKİ) saptandı, öyküde kadın-doğum hastalıkları, ailede diyabet, iri bebek doğurma öyküsü olup olmadığı sorgulandı, magnezyum eksikliğinin klinik belirtileri araştırıldı. Gebelerin beslenmesi Amerikan Gıda ve Beslenme Kurulu referanslarına göre değerlendirildi, HgbAlc, magnezyum, kalsiyum, böbrek ve karaciğer fonksiyon testleri, amilaz değerleri ve tam idrar ana¬lizi yapıldı. Veriler korelasyon ve çoklu doğrusal regresyon analiz¬leri ile test edildi. Bulgular: Ortalama yaş, gravite sayısı, parite sayısı ve BKİ; hasta grubunda anlamlı olarak yüksekti (p<0.05). Hasta grubunda gebelik öncesi BKİa30 olanların oranı %30.2, VKİ=25-29.9 olanların oranı %50.9'du. Günlük ortalama magnezyum alımı ve serum magnezyum düzeyleri açısından gruplar arasında anlamlı fark yoktu (sırasıyla, p=0.234, p=0.337). Bulantı ve kusma hikâyesi olanların günlük ortalama magnezyum alımı istatistiksel olarak anlamlı derecede yüksekti (sırasıyla p=0.001, p=0.006). Serum magnezyum düzeyi ile HbA1c ve serum kalsiyum düzeyi arasında istatistiksel olarak anlamlı bir ilişki bulunmadı (sırasıyla p=0.444, p=0.614). Sonuç: Gebelik döneminde serum magnezyum düzeylerinde hafif düşüş olmakla birlikte, bu çalışmada gestasyonel diyabeti olan ge¬belerle olmayanlar arasında magnezyum alımı veya serum mag¬nezyum düzeyleri arasında fark bulunamadı.
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