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Sigarayı Bırakmada Antidepresanların Rolü

THE ROLE OF ANTIDEPRESSANTS IN SMOKING CESSATION

Journal Name:

  • Türkiye Aile Hekimliği Dergisi

Publication Year:

  • 2005

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
Smoking is the most frequent and preventable cause of premature death. Smoking causes a wide range of disorders, including chronic obstructive pulmonary disease, coronary heart disease, stroke, peripheral vascular disease, peptic ulcer disease and many types of cancer. Worldwide, 3 million people die annualy due to smoking related disorders. Over the last decade, smoking rates have decreased consistently in the general population. It is now widely accepted that nicotine is the principal cause of tobacco consumption, and nicotine preparations are extensively used as aids during smoking cessation. However many of the medical nicotine preperation do not provide to the abstinent smoker an adequate susbstitute for nicotine inhaled in tobacco smoke. As many smokers relapse within a relatively short time, its effective¬ness is disappointing. Sustained-release bupropion is the first non-nicotine pharmacological treatment approved for smoking cessation.
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Abstract (Original Language): 
Sigara içme, erken ölümlerin en sık ve önlenebilir nedenidir. Kronik obstrüktif akciğer hastalığı, koroner kalp hastalığı, inme, peri-ferik vasküler hastalıklar, peptik ülser ve çok sayıda kanser sigara içme sonucu meydana gelir. Dünyada her yıl 3 milyon kişi sigara içimiyle ilişkili hastalıklar nedeniyle ölmektedir. Son on yılda genel popülasyonda sigara içme oranı sürekli olarak azalmıştır. Genel olarak nikotinin tütün içiminin temel nedeni olduğu kabul edil¬mekte, tıbbi nikotin preperatları sigara bırakma tedavisinde yaygın olarak kullanılmaktadır. Buna rağmen bir çok medikal nikotin pre-peratı sigara yoksunluğundaki içicilerde nikotinin yerini yeterli de¬recede alamamaktadır. Bir çok sigara içicisinin kısa bir süre içinde tekrar başlaması nedeniyle etkinliği hayal kırıcıdır. Sürekli salınımlı bupropion sigara bırakmakta onaylanmış ilk nikotin dışı farmakolojik tedavidir.
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32-36
  • Turkish

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