You are here

THE HISTOPATHOLOGIC CORRELATION OF DILATATION & CURETTAGE AND HYSTERECTOMY SPECIMENS IN PATIENTS WITH POSTMENOPAUSAL BLEEDING

Journal Name:

Publication Year:

Abstract (2. Language): 
The aim of this study was to evaluate the consistency of preoperative and postoperative ttİsto-pathological findings in postmenopausal patients vvith bleeding. 42 postraenopausal women presenting wİth the compİaİnt of bleeding to whom both dilatation&curettage (D&C) and hys-terectomy were performed were examined retrospectİvely regarding their pathology results. Each paticnt's D&C and hysterectomy pathology result were compared and the consistency of preoperative and postoperative findings were evaluated by the correlation analyses. Histopath-ologic evaluation of specimens were performed by the pathologîsts specialized on gyneacolog-ic pathology and endometrial hyperplasias were described by terms endorsed by the International Society of Gynecological Pathologîsts. Pathology examination of D&C and hysterectomy specimens of 42 mcnopausal patients were studied and the consistency of preoperative and postoperative findings weıe examined. The distribution of preoperative diagnosis was 16 patients (38%) with irregular proliferative endometrium, 14 patients (33%) wİth sİmple hyper-plasia, 4 patients (9.5%) with complex hyperplasia without atypia, 3 patients (7.14%) with complex hyperplasia with atypia and 3 patients (7.14%) with endometrial polyp. In one patient (2.38%), it was reported that there was no material in D&C and in one patient (2.38%) endometrium cancer was found preoperativcly. The distribution of postoperative diagnosis was 16 patients (38%) with irregular proliferative endomelrium, 12 patients (28.5%) with simple hyperplasia, 5 patients (11.9%) vvith complex hyperplasia without atypia, 4 patients (9.5%) with complex hyperplasia with atypia, 3 patients (7.14%) wilJı endometrium cancer and 2 patients (4.76%) wi£h endometrial polyp. The correlation analysis of these variables has shown that there was a positive correiation between variables (correlalion coefficicnt: 0.98). This means that the preoperative diagnosis correlates positively with the postoperative diagnosis. Howev-er, when preoperative diagnosis group was subgrouped and reanalysed, it seems that whilc the preoperative diagnosis gets worse, D&C may skip the real and much worse pathology. Gener-ally preoperative D&C endometrial pathology findings positively correlate with post operative hysterectomy pathology results. However, as the real pathology gets worse, D&C seems to un-derdiagnose the real pathology and İn cases vvith complex hyperplasia vvilh or vvithout atypia, a second D&C or hysterescopic evaluation in order to get biopsies from suspicİous arcas may be recommended.
218-223

REFERENCES

References: 

1. Chambers )T, Chambcrs SK: Endometrial sampling: When? Where? VVhy? With What? Clin Obstet Gynecol 1992; 3528.
2. Gordoü M.D., Ireland K.: Pathology of hyperplasia and carcinoma of the endometrium. Semin. Oncol. 1994; 21:64.
Çitil t., Saygılı H., Çakır Ç., Topuz S.
3. Grimes DA. Diagnostic dilation and curettage: A reap-praisal. Am J Obstet Gynecol 1982; 142: I.
4. Gündem G, Sedag F, Kazandı M et al: Preoperative and postoperative correlation of histopathological fındmgs in cases of endometrial hyperplasia. Euro J Gynecof Onca 2003; 24:330.
5. Hunter JE, Tritz DE, Howell MG, et al: The prognostic and therapeûtic implications of cytologîc atypia in patients vvith endometrial hyperplasia. Gynecol Oncol 1994; 55:66.
6. Kauniiz AM, Masciello A, Ostrovvüki M et al: Compari-son of endometrial biopsy vvith endometrial carcinoma and hyperplasia: a metaanalysis. Cancer 2000; 89:1765.
7. Kurman RJ, Kaminski PF, Norris HJ: The behaviour of endometrial hyperplasia: A long term study of untreated 170 patients Cancer 1985; 56: 403.
8. MacMahon B: Risk factors for endometrial cancer. " Gynecol Oncol 1974;2:122-129
9. Randaîl T.C., Kurman R.J.: Progestİn ıreatment of atypical hyperplasia and well differentiated carcinoma of Ihe endometrium in women under age 40. Obstet Gynecol., 1997; 90:434.
10. Stelmachovv J: The role of hysterescopy in gynecologic oncology. Gynecol Oncol 1982; 14:392.
11. Stock RJ, Kanbour A: Prehysterectomy curettage: an evaluation Obstet Gynecol 1975; 45: 537.

Thank you for copying data from http://www.arastirmax.com