You are here

Home » Content

ISOLATION AND CHARACTERIZATION OF TWO ALKALOIDS FROM THE ETHANOLIC EXTRACT OF NYCTANTHES ARBOR-TRISTIS L. LEAVES

Journal Name:

  • Advance Research in Pharmaceuticals and Biologicals

Publication Year:

  • 2012

Key Words:

Author Name
Abstract (2. Language): 
The objective of the present study was to isolate and characterize phytoconstituents from the ethanolic extract of Nyctanthes arbor-tristis L. leaves. By of the ethanolic extract of Nyctanthes arbor-tristis L., two alkaloidal compounds fractionated and isolated by column chromatography and further structures of these compounds were determined on the basis of spectral and chemical studies. It comprised two novel compounds i.e. 1- (8-Hydroxy-7-((4-nitrophenyl) (phenyl amino) methyl) quinoline-3-yl) propan-2-one and 2- (8-Hydroxy-7-((4-nitrophenyl) (phenyl amino) methyl) quinoline-3-yl) acetic acid. Structures of all the isolated compounds were elucidated by spectroscopic methods like IR, NMR and Mass spectrometry.
Bookmark/Search this post with
FULL TEXT (PDF): 
PDF icon arastrmx_160852_4_pp_342-344.pdf
  • 2
342-344
  • English

REFERENCES

References: 

1. K. M. Nadkarni. Indian Materia Medica. Third
edition, Vol. I, Bombay: Bombay Popular Prakashan
Pvt. Ltd., 1982, pp. 115-116.
2. K. R. Kirtikar, B. D. Basu. Indian Medicinal Plants.
Vol. VII, New Delhi, Sri Satguru Publications, 2000,
pp. 2110-2113.
3. R. S. Saxena, B. Gupta, S. Lata. Tranquillizing,
antihistaminic and purgative activity of Nyctanthes
arbortristis leaf extract, J Ethanopharmacol 81: 321-
325 (2002).
4. W. D. Ratnasooriya, JRAC Jayakody, M. G.
Hettiarachchi ADI. Sedative effects of hot flower
infusion of Nyctanthes arbo-tristis on rats, Pharm
Biol 43: 140-146 (2005).
5. S. Das, D. Sasmal, S. P. Basu. Evaluation of CNS
depressant activity of different plant parts of
Nyctanthes arbortristis Linn., Indian J Pharm Sci 70:
803-806 (2008).
6. S. A. Nirmal, S. C. Pal, S. C. Mandal. Antiasthmatic
activity of Nyctanthes arbortristis leaves, Lat Am J
Pharm 30(4): 654-660 (2011).
7. Charak, Samhita : Shri Gulabkunverba Ayurvedic
Society, Jamnagar, vol. V, Ayurvedic Mudranalaya,
Jamnagar,1949: 23-24.
8. R. N. Chopra, I. C. Chopra, K. L. Handa and L. D.
Kapur, Chopra’s Indigenous drugs of India, second
ed.. UN Dhar and sons, Calcutta, 1958:408.
9. S. A. Nirmal, S. C. Pal, S. C. Mandal, A. N. Patil.
Analgesic and anti-inflammatory activity of β-
sitosterol isolated from Nyctanthes arbortristis
leaves, Inflammopharmacology 2011 (In press).
10. A. K. Shukla, S. Patra, V. K. Dubey. Deciphering
molecular mechanism underlying antileishmanial
activity of Nyctanthes arbortristis, an Indian
medicinal plant, J Ethnopharmacol 134(3): 996-998
(2011).
11. R. K. Das, N. Gogoi, U. Bora. Green synthesis of gold
nanoparticles using Nyctanthes arbortristis flower
extract, Bioprocess Biosyst Eng 34(5): 615-619
(2011).
12. S. Das, D. Sasmal, S. P. Basu. Evaluation of CNS
Depressant Activity of Different Plant parts of
Nyctanthes arbortristis Linn., Indian J Pharm Sci
70(6): 803-806 (2008).
13. S. Das, D. Sasmal, S. P. Basu. Anti-inflammatory and
antinociceptive activity of arbortristoside-A, J
Ethnopharmacol 116(1): 198-203 (2008).
14. B. Rathore, B. Paul, B. P. Chaudhury, A. K. Saxena, A.
P. Sahu, Y. K. Gupta. Comparative studies of
different organs of Nyctanthes arbortristis in
modulation of cytokines in murine model of
arthritis, Biomed Environ Sci 20(2): 154-159
(2007).
15. P. Gupta, S. K. Bajpai, K. Chandra, K. L. Singh, J. S.
Tandon. Antiviral profile of Nyctanthes arbortristis
L. against encephalitis causing viruses, Indian J Exp
Biol 43(12): 1156-1160 (2005).

Thank you for copying data from http://www.arastirmax.com