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KEMİK SEMENTININ (BONE CEMENT) KEMİK VE ÇEVRE DOKUSU ÜZERİNE ETKİSİNİN DENEYSEL ARAŞTIRILMASI

THE EXPERIMENTAL INVESTIGATION OF THE EFFECT OF BONE CEMENT ON BONE AND SURROUNDING TISSUES

Journal Name:

  • İstanbul Üniversitesi Diş Hekimliği Fakültesi Dergisi

Publication Year:

  • 1992

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
In our study, the effect of bone cement on bone and surrounding tissues was experimentally investigated. Thirty male Wistar Albino rats, six months old and weighing 200+20 gr. were used in the experiment. The rats were given ether anesthesia and mucoperiosteal flaps were raised in their right mandibles. Bone cavities, under the irrigation with saline solution were prepared with the aid of low speed drill. The mucoperiosteal flaps were, then, sutured with 410 cutgut. The rats were sacrified on the 10th, 20th. and 30th. days. After the fixation in % 30 formaide hid, the materials were decalcified in a formic aid solution tamponaded with sodium citrate. The sections were stained with Hematoxy-len-Eosin and they were histopalhologically investigated. At the end of our study, it was found that, instead of a complete contact, a thin layer of fibrous tissue formed between the bone and the cement placed in the bone. Also it was concluded that, both the polymerization heat and the remnants of the monomer have necrotizing effect on the bone and the surrouding tissues.
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Abstract (Original Language): 
Çalışmamızda kemik sementinin (bone cement) kemik ve çevre dokusu üzerine olan etkisi deneysel olarak incelendi. Araştırmada 30 adet, 200+20 gr. ağırlığında, 6 aylık, erkek Wistar Albino sıçanlar kullanıldı. Sıçanlar ether ile uyutularak, sağ alt çenelerinde mukoperiostal flap kaldırıldı. Düşük devirli mikromotor ile serum fizyolojik ile soğutularak kemik kavitesi meydana getirildi. Homojen olarak karıştırılan kemik sementi açılan kemik kavitelerine yerleştirildi. Mukopcrioslal flap 4/0 katgüt ile yerine dikildi. Denekler 10., 20. vc 30. günlerde öldürüldüler. Elde edilen materyaller % 10'luk formaide f'ikse edildikten sonra, Sodyum Sitrat ile tamponlanmış formik asit çözeltisinde dekalsifiye edildiler. Kesitler Hematoksilen+Eosin ile boyandılar ve histopatolojik yönden incelendiler. Araştırmamızın sonucunda, kemik içine uygulanan sement ile kemik arasında tamamen bir kaynaşma olmayıp, arada ince bir fibröz doku oluştuğu, polimerizasyon esnasında ortaya çıkan ısının ve artık monomerin kemik ve çevre dokusu üzerine nekroz yapısı etkisi olduğu saptandı.
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  • Turkish

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