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The role of Medial Preoptic Area in reproductive behavior of male rats

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Abstract (2. Language): 
Introduction: It is known that medial Preoptic area (mPOA) of the forebrain exerts a significant influence on reproductive behavior of an animal. The mPOA occupies a key position in the central nervous regulation of male sex behavior. The present study was planned to see whether discrete electrolytic lesions in male rats could have functional deficits in motivational and/or consummatory sexual behavior. Methods: Thirty adult laboratory bred male Wistar rats weighing around 175 to 240 gms with average age 200 days were selected for the experiment. They were divided into two groups - control group (N=15) and experimental group (N=15). Sexual behavior was observed before lesions and after lesions. Observations and Result: In lesioned animals sex drive score decreased as compared to control group, also grooming latency, pursuit latency, mount latency, intromission latency and ejaculation latency significantly increased. While grooming frequency, pursuit frequency, mount frequency and intromission frequency significantly decreased. Conclusion: The present work elucidates that bilateral electrolytic lesions in mPOA in adult male rats severely disrupts the precopulatory and copulatory responses.
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