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FENİTOİNLE İLİŞKİLİ DRESS SENDROMU: OLGU SUNUMU

DRESS SYNDROME ASSOCIATED WITH PHENYTOIN: CASE REPORT

Journal Name:

  • Online Türk Sağlık Bilimleri Dergisi

Publication Year:

  • 2016

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
DRESS syndrome is an acute drug related hypersensitivity reaction characterized with acute onset of fever, skin rash and potentially life-threatening internal organ involvement. The diagnosis of DRESS syndrome is difficult because of the variety of skin findings and different organ involvements. Early diagnosis and treatment of patients with DRESS syndrome is important because of high mortality risk. In this article, a case with DRESS syndrome due to use of phenytoin is presented and it has been requested to take attention to DRESS syndrome.
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Abstract (Original Language): 
DRESS Sendromu akut başlangıçlı, ateş, cilt döküntüsü ve iç organ tutulumu ile karakterize yaşamı tehdit edebilen ilaca bağlı akut bir hipersensitivite reaksiyonudur. Farklı organ tutulumları ve deri bulgularının çeşitliliği nedeniyle DRESS Sendromunun tanısı zordur. Yüksek mortalite riski taşıyan bir durum olması sebebiyle DRESS sendromu hastalarının erken tanınması ve tedaviye erken başlanması önemlidir. Bu yazıda fenitoin kullanımına bağlı olarak gelişen bir DRESS Sendromu vakası sunularak konuya dikkat çekilmek istenmiştir.
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  • Turkish

REFERENCES

References: 

1- Walsh SA, Creamer D: Drug reaction with eosinophilia and systemic symptoms (DRESS): a clinical update and review of current thinking. Clin Exp Dermatol 2010;36:6-11.
2- Kaswala DH. Drug Rash with Eosinophilia and Systemic Symptoms Syndrome Due to Anti-TB Medication. J Family Med Prim Care. 2013; 2(1): 83–85.
Online Türk Sağlık Bilimleri Dergisi 2016, Cilt 1, Sayı 2, 23-26 Murat YÜCEL
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3- Oelze LL, Pillow MT. Phenytoin-induced drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome: a case report from the emergency department. J Emerg Med. 2013;44(1):75-8.
4- Criado PR, Criado RFJ, Avancini JM, Santi CG. Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)/Drug-Induced Hypersensitivity Syndrome (DIHS): a review of current concepts. An Bras Dermatol 2012; 87:435-49.
5- Michel F, Navellou JC, Ferraud D, et al. DRESS syndrome in a patient on sulfasalazine for rheumatoid arthritis. Joint Bone Spine 2005;72:82-5.
6- Bocquet H, Bagot M, Roujeau JC. Drug-induced pseudolymphoma and drug hypersensitivity syndrome (Drug Rash with Eosinophilia and Systemic Symptoms: DRESS). Semin Cutan Med Surg. 1996;15(4): 250-7.
7- Choudhary S, McLeod M, Torchia D, Romanelli P. Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome. J Clin Aesthet Dermatol. 2013; 6(6): 31–37.

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