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Bilateral overektomi ve unilateral nefrektominin diğer böbrek dokusu üzerine olan etkileri

Effects of bilateral overektomy and unilateral nephrectomy on other renal tissue

Journal Name:

  • Selçuk Tıp Dergisi

Publication Year:

  • 2002

Key Words:

Keywords (Original Language):

Author NameUniversity of Author
Abstract (2. Language): 
The renin angiotensin system is thought to be modulated by gonadal steroids. After unilateral nephrectomy and unilateral nephrectomy + bilateral ovariectomy, occured changes were investigated in this study. Right nephrec-tomized and rigth nephrectomized + bilateral ovariectomized femaie rats ieft kidneys were examined histopatho-logically after four week. Severe inflammatory reaction was observed in only nephrectomized rats after four week. Moreover acut renal ischaemia was observed in the unilateral nephrectomized + total ovariectomized rats İeft kid-ney. Our results showed that gonadal steroids may have a role in modulating acut renal ischaemia.
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Abstract (Original Language): 
Renin antiotensin sisteminin gonada! steroidlerle düzenlendiği düşünülmektedir. Bu çalışmada unilateral nefrekto-mi ve uniiatreal nefrektomi + bilateral ovarektomi sonrasında diğer böbrek dokusunda meydana gelen histopa-tolojik değişiklikler araştırıldı. Dişi sıçanlara sağ nefrektomi ve bilateral overektomi uygulandı. Sol böbrekler ise bir ay sonra histolojik incelemelerde bulunmak üzere alındı. Sadece nefrektomi uygulaması, böbrek dokusunda, şiddetli inflamatuvar reaksiyon geliştirdi. Overektomi + unilateral nefrektomi, akut renal iskemiye neden oldu. Iskemi sonucu böbrek dokusunda hasar gelişti. Sonuçlarımız gonadal steroidlerin, akut renal iskemiyi düzenleyen bir role sahip olduğunu gösterdi.
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  • 2
83-88
  • Turkish

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