You are here

Home » Content

Farklı Türdeki Egzersizlerin Nitrik Oksit Üzerine Akut ve Kronik Etkileri

Acute and Chronic Effects of Different Types of Exercises on Nitric Oxide

Journal Name:

  • Selçuk Üniversitesi Beden Eğitimi ve Spor Bilim Dergisi

Publication Year:

  • 2011

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
In relation to diverse factors exercise may cause different effects to our body. The cause for these factors is the intensity and duration of the exercise. This study aims to examine the relationship between different exercise types with the element nitric oxide which is effective in relieving the veins by expanding them. The study material was composed of 10 sportsmen from Kayak National Team. The effect of maximal burden on NO level was investigated by applying regular medium hard physical activity program on these sportsmen, 30-60 minutes a day, 3 times a week for a month following a speed test (10x20mt) applied and following the exercise program. Blood samples were taken shortly following the test and while resting. One month later blood samples were taken again and the same test was applied. Prior to the program while the serum NO levels at resting was 18.48  1.63U/mL following the speed test was determined to be 14.86  1.51 U/mL. After the program while the serum NO levels at resting was 30.56  2.18 U/mL following the speed test was determined to be 20.22  1.65 U/mL. In accordance with the outcome of the results on maximal load the serum NO level showed a significant statistical decrease, following a four week regular exercise a significant statistical increase, and whereas a significant statistical increase between maximal exercise and workout and a statistical significant interaction between maximal exercise and workout was seen. As a result, by increasing the NO level, regular and medium hard physical activities may result expansion in the veins which helps ease cardiovascular system by increasing the NO level. However, it was observed that excessive exhausting maximal exercise decreased the NO level in the body. This reason can be explained with the excessive use of the NO in the veins due to increasing blood pressure.
Bookmark/Search this post with
Abstract (Original Language): 
Birçok etkenle ilişkili olarak egzersiz vücudumuzda farklı etkilere neden olur. Bu etkenlere bir sebepte egzersizin şiddeti ve süresidir. Bu çalışmada farklı türdeki egzersizler ile damarları genişleterek rahatlanmasında etkili bir madde olan Nitrik Oksit (NO) arasındaki ilişkinin incelenmesi amaçlanmıştır. Çalışmanın örneklemini, Kayak Milli Takımından 10 erkek sporcu (yaş 22.90  4.33 yıl) oluşturdu. Bu sporculara bir ay, haftada üç gün, günde 30-60 dk orta şiddette düzenli fiziksel aktivite programı uygulatılarak egzersizin, program öncesinde ve sonrasında sürat (10x20mt) testi yaptırılarak maksimal yüklenmenin NO seviyesi üzerine etkisi araştırıldı. İstirahat durumunda ve testten hemen sonra kan numuneleri alındı. Bir ay sonra tekrar aynı test ve örnek kan alımları yapıldı. Program öncesinde; dinlenmede serum NO düzeyleri 18.48  1.63U/mL iken sürat testi sonrası 14.86  1.51 U/mL tespit edilmiştir. Program sonrasında; dinlenmede serum NO düzeyleri 30.56  2.18 U/mL iken sürat testi sonrası 20.22  1.65 U/mL tespit edilmiştir. Çıkan sonuçlar doğrultusunda, maksimal yüklenmelerde serum NO seviyesinde istatistiksel olarak anlamlı bir düşüşe (p<0.001), dört haftalık düzenli egzersiz sonrasında istatistiksel olarak anlamlı bir artışa (p<0.001) ve maksimal egzersiz ile antrenman arasında ise istatistiksel olarak anlamlı bir etkileşim görülmüştür (p<0.05). Sonuç olarak, düzenli ve orta şiddetle yapılan fiziksel aktiviteler NO seviyesini artırarak damarların genişlemesine ve kardiyovasküler sistemin rahatlamasına neden olabilir. Ancak vücudu aşırı yoran maksimal egzersizlerde, NO seviyesinde düşüş görülmüştür. Buna neden olarak, artan kan basıncından dolayı NO’ in damarlarda fazla kullanılmasından kaynaklandığı söylenebilir.
FULL TEXT (PDF): 
PDF icon arastirmax-farkli-turdeki-egzersizlerin-nitrik-oksit-uzerine-akut-kronik-etkileri.pdf
  • 1
26-30
  • Turkish

REFERENCES

References: 

1. Aladağ A.M, Turkoz, Y, Ozerol H.İ, Nitrik oksit ve
nörofizyopatolojik etkileri. Turkiye Klinikleri J Med Sci
2000; 20.107–111.
2. Andrea CP, Cesar O, Julio GP, Ana F, Luzdivina V,
Ana IA, Quantitative assessment of nitric oxide in
rat skeletal muscle and plasma after exercise. Eur J
Appl Physiol, 2002; 88: 189–191.
3. Balon T, Nadler J, Nitric oxide release is present from
incubated skeletal muscule preperations. Journal Appl
Physiol, 1994; 77: 2519-2521.
4. Chandan KS, Handbook of oxidants and antioxidants
in exercise. Elsevier Science B.V.All rights reserved.
2000.
5. Christopher KD, David NP, Niki MD, and Michael J,
Role of nitric oxide in exercise hyperaemia during
prolonged rhythmic handgripping in humans. Journal
of phsiolojy, 1995; 259-265.
6. Cuzzolın L. Lussıgnolı S. Crıvellente F. Adamı A.
Schena F. Bellavıte P. Brocco G. Benonı G. Influence
of an acuteexercise onneutrophil and platelet adhesion,
nitric oxide plasma metabolites in inactive and active
subjects. Int J Sports Med, 2000; 21(4): 289-293.
7. Delp MD, Mcallister RM, Laughlin MH, Exercise
trainingalters endothelium-dependent vasoreactivity of
rat abdominalaorta. J Appl Physiol, 1993; 75(3): 1354-
1363.
8. Franco L, Doria D, Mattiucci F, Effect of acute
exercise on plasma nitric oxide level in humans.
Medical principles and practice. Apr-Jun, 2001; 10(2):
106-109.
9. Green LC, Wagner DA, Glogowski J, Skipper PL,
Wishnok JS, Tannenbaum SR, Analysis of nitrate,
nitrite and [‘5N]nitrate in biological fluids. Anal
Biochem, 1982; 126: 131-138.
10. Güllü E. Sedanterlerde ve dayanıklılık sporcularında
maximal ve submaximal egzersiz sonrası oluşan
oksidan stres ve antioksidan düzeylerinin
karşılaştırılması. Doktora Tezi, Ankara, 2007.
11. Higashi Y, Sasaki S, Sasaki N, Nakagawa K, Ueda
T,Yoshimizu A, et al. Daily aerobic exercise improves
reactivehyperemia in patients with essential
hypertension. Hypertension, 1999; 33: 591-597.
12. Ji LL, Exercise at old age, does it increase or alleviate
oxidative stress. Annals of the New York Academy of
Science, 2000; 236-247.
13. Jungersten L, Ambrıng A, Wall B, and Wennmalm A,
Both physical fitness and acute exercise regulate nitric
oxide formation in healthy humans. J Appl Physiol,
1997; 82: 760-764.
14. Kayaalp O, Santral sinir sistemi farmakolojisinin
temelleri. Rasyonel tedavi yönünden tıbbi farmakoloji.
9.baskı, Hacettepe-Taş Kitapçılık Lmt. Şti. Ankara.
2000; 1(54): 757–764.
15. Kingwell BA, Nitric oxide-mediated metabolic
regulationduring exercise: effects of training in health
and cardiovasculardisease. Faseb J, 2000; 14: 1685-
1696.
16. Kingwell BA, Nitric Oxide as a metabolic regulator
during exercise: effects of training in health and
disease. Clin Exp Pharmacol Physiol. 2000; 27(4): 239
– 250.
17. Kuru O, Sentürk UK, Demir N, Yesilkaya A,Ergüler
G, Erkiliç M, Effect of exercise on bloodpressure in
rats with chronic NOS inhibition. Eur J Appl Physiol,
2002; 87: 134-140.
18. Kuyumcu A, Düzgün AP, Özmen, MM, Besler HT.
Travma ve enfeksiyonda nitrik oksidin rolü. Ulus.
Travma Dergisi, 2004; 10(3): 149–159.
19. Lawson DL, Liying C, and Jawahar LM, Effects of
exercise–ınduced oxidative stress on nitric oxide release
and antioxidant activity. By Exerpta Medica, İnc, 1997.
20. Louis J. Ignarro.(çeviri) Öztürk Ö, NO ile kalp
hastalıklarına son. Özbay yayıcılık, İstanbul, 2007.
21. Maeda S, Miyauchi T, Kakiyama T, Sugawara J, et al,
Effect of exercise training of 8 weeks and detraining on
plasma levels of endothalium-derived factors,
endothelin-1 and nitric oxide, in healthy young humans.
Life Sciences, 2001; 69 (9): 1005-1006.
22. Matthew BG, Jourdheuıl D, Wınk DA, Nitric oxide I.
Physiologicalchemistry of nitric oxide and its
metabolites: implications ininflammation. Am.
J.Physiol, 1999; 276(2): 315-321.
23. Palmer RMJ, Ferrıge AG, Moncada S, Nitric oxide
release accounts fort pense he biological activity of
endothelium-derived relaxing factor. Nature, 1993;
327:524–536
24. Pehlivan A, Fitness salonlarında risk faktörü taşıyan
kişilerde uygulanabilecek, interval prensipli aerobik
antrenman programı. Spor Araştırmaları Dergisi, 2000;
4: 1-6.
25. Radak Z, Pucsok S, Mecseki T, Ferdinandy P. Muscle
Sorenesinduced reduction in force generation is
accomppanied by increased nitric oxide content and
DNA damage in skeletal muscle. Free rad. Biol. Med,
1999; 26: 1059- 1063.
26. Roberts K, Barnard RJ, Jasman A, Balon TW, Acute
exerciseincrease nitric oxide synthase activity in skeletal
muscle. Am JPhysiol, 1999; 277: E390-E394.
27. Sessa WC, Pritchard K, Seyedi N, Wang J, Hintze TH,
Chronic exercise in dog increase coronary vascular
nitric oxideproduction and endothelial cell nitric oxide
synthase geneexpression. Circ Res, 1994; 74: 349-353.
28. Schmidt HW, Warner TD, Nakane M, Forstermann U,
Murad F, Regulation and subcellular location of
nitrogen oxide synthases in RAW264.7 macrophages.
Mol Pharmacol, 1992;41: 615-624.
29. Tüzün M, Obezite: Tanım, sıklık, sınıflandırma tipleri,
dereceleri ve komplikasyonları. obezite, Nobel Tıp
Kitapevleri Limited Şirketi, 1995: 1-20.

Thank you for copying data from http://www.arastirmax.com