Buradasınız

Klinikte Parsiyel Mol Hidatiform Tanısı Alan Plasental Mezenkimal Displazi: Olgu Sunumu

Placental Mesenchymal Dysplasia Clinically Diagnosed As Partial Hydatidiform Mole: Case Report

Journal Name:

Publication Year:

Abstract (2. Language): 
Placental mesenchymal dysplasia is a rare placental abnormality. Placenta is found to be enlarged with cystic villi and dilated thick vascular structures. Importance of this abnormality is the clinical and morphological similarity to the partial hydatidiform mole and presentation with Beckwith- Wiedemann syndrome. Our case was diagnosed as partial hydatidiform mole in her rutin pregnancy controls. This is the 20. case in literature that had not any extra-placental abnormality.
Abstract (Original Language): 
Plasental mezenkimal displazi nadir görülen bir plasenta anomalisidir. Plasenta normalden büyük olup kistik villuslar ve genişlemiş kalın duvarlı damarlar mevcuttur. Bu anomalinin önemi klinik ve patolojik olarak parsiyel mol hidatiforma benzemesi ve genellikle Beckwith- Wiedemann sendromu ile birliktelik göstermesidir. Doğum öncesi rutin takiplerinde parsiyel mol hidatiform tanısı alan plasental mezenkimal displazi olgusu, plasenta dışında anomalisi olmayan 20. vaka olması ve nadir görülmesi nedeniyle sunulmuştur.
207-210

REFERENCES

References: 

1. Arizawa M, Nakayama M. Suspected involvement of the X chromosome in placental mesenchymal dysplasia. Congenit Anom (Kyoto) 2002; 42(4):309–17
2. Paradinas FJ, Sebire NJ, Fisher RA, Rees HC, Foskett M, Seckl MJ, Newlands ES. Pseudo-partial moles: placental stem vessel hydrops and the association with Beckwith-Wiedemann syndrome and complete moles. Histopathology 2001; 39(5):447–54.
3. Matsui H, Iitsuka Y, Yamazawa K, Tanaka N, Mitsuhashi A, Seki K, Sekiya S. Placental mesenchymal dysplasia initially diagnosed as partial mole. Pathol Int 2003; 53(11):810–13.
4. Furuhashi M, Oda H, Nakashima T. Hydrops of placental stem villi complicated with fetal congenital adrenal hyperplasia. Arch Gynecol Obstet 2000; 264(2):101–4.
5. Ohyama M, Kojyo T, Gotoda H, Sato T, Ijiri R, Tanaka Y. Mesenchymal dysplasia of the placenta. Pathol Int 2000; 50(9):759–64.
6. Chan YF, Sampson A. Placental mesenchymal dysplasia: a report of four cases with differentiation from partial hydatidiform mole. Aust N Z J Obstet Gynaecol 2003; 43(6):475–9.
7. Jauniaux E, Nicolaides KH, Hustin J. Perinatal features associated with placental mesenchymal dysplasia Placenta 1997;18(8):701–6.
8. Lage JM. Placentomagaly with massive hydrops of placental stem villi, diploid DNA content, and fetal omphaloceles: possible association with Becwith- Wiedeman syndrome. Hum Pathol 1991; 22(6):591–7.
9. Moscoso G, Jauniaux E, Hustin J. Placental vascular anomaly with diffuse mesenchymal stem villous hyperplasia. A new clinico-pathological entity? Pathol Res Pract 1991;187(2–3):324–8.
10. Sander CM. Angiomatous malformation of placental chorionic stem vessels and pseudo-partial molar placentas: report of five cases. Pediatr Pathol 1993;13(5):621–33.
11. Hojberg KE, Aagaard J, Henriques U, Sunde L. Placental vascular malformation with mesenchymal hyperplasia and a localized chorioangioma. A rarity simulating partial mole. Pathol Res Pract 1994;190(8):808–13.
12. Chen CP, Chern SR, Wang TY, Huang ZD, Huang MC, Chuang CY. Pregnancy with concomitant chorangioma and placental vascular malformation with mesenchymal hyperplasia. Hum Reprod 1997; 12(11):2553–56.
13. Mulc AD, Stallings SP, Salafia CM. Elevated maternal serum alpha-fetoprotein, umbilical vein varix, and mesenchymal dysplasia: are they related? Prenat Diagn 2006;26(8):659–61.
14. Pham T, Steele J, Stayboldt C, Chan L, Benirschke K. Placental mesenchymal dysplasia is associated with high rates of intrauterine growth restriction and fetal demise: A report of 11 new cases and a review of the literature. Am J Clin Pathol 2006;126(1):67–78
15. Gibson BR, Muir-Padilla J, Champeaux A, Suarez ES. Mesenchymal dysplasia of the placenta. Placenta 2004; 25(7):671–2.
16. Takayama M, Soma H, Yaguchi S, Funayama H, Fujiwara K, Irie H, Yamabe S. Abnormally large placenta associated with Beckwith-Wiedemann syndrome. Gynecol Obstet Invest 1986;22(3):165–8.
17. Cohen MC, Roper EC, Sebire NJ, Stanek J, Anumba DO. Placental mesenchymal dysplasia associated with fetal aneuploidy. Prenat Diagn 2005; 25(3):187–92.
18. Benirschke K and Kaufmann P. Pathology of theHuman Placenta; Springer Verlag. New York: RN Baergen. 2005. ISBN 0-387-22089-5

Thank you for copying data from http://www.arastirmax.com