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FULMİNAN KARACİĞER YETERSİZLİĞİ: ETYOLOJİK, KLİNİK VE PROGNOSTİK ÖZELLİKLERİ

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Abstract (2. Language): 
Fulminant hepatic failure is a clinical syndrome with high mortality, characterized by the rapid onset of severe hepatocellular dysfunction, often accompanied by hepatic encephalopathy, in the absence of preexisting liver disease. Although many reasons may cause fulminant hepatic failure, the most common causes of the syndrome are hepatitis viruses, toxin and drugs. The mortality of fulminant hepatic failure is still high despite improvements in the medical emergency care and liver transplantation. This article examines the etiological, clinical and prognostic features of the syndrome as well as its complications.
Abstract (Original Language): 
Fulminan karaciğer yetersizliği önceden herhangi bir karaciğer hastalığı bulunmaksızın karaciğer fonksiyonlarının aniden ve ciddi bir şekilde bozulmasıyla karakterize, sıklıkla hepatik ensefalopatinin eşlik ettiği, potansiyel olarak geri dönüşümlü olabilen ancak mortalitesi oldukça yüksek bir klinik sendromdur. Etyolojide birçok neden yer alabilmesine karşın, genellikle en sık görülen nedenler arasında hepatit virüsleri ile toksin ve ilaçlar bulunmaktad ır. Yoğun bakım koşulları ve karaciğer transplantasyonu konusundaki gelişmelere karşın hastalığın mortalitesi hayli yüksektir. Bu yazı- da fulminan karaciğer yetersizliğinin etyolojik, klinik ve prognostik özellikleri ile komplikasyonlar ı irdelenmiştir.
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