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Bazal Hücreli Karsinomada Etyolojik Faktörlerin Araştırılması

The Investigation Of Etiological Factors In Basal Cell Carcinoma

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Abstract (2. Language): 
The Investigation Of Etiological Factors In Basal Cell Carcinoma Purpose: In this study, we aimed to investigate the role of the etiological factors in patients with basal cell carcinoma (BCC) in which the diagnosis were confirmed clinically and histopathologically. Materials and methods: We investigated the role of life styles and environmental factors in etiology, of 58 BCC patients and 45 control cases. Results: The difference between two groups was statistically significant concerning the skin type, sun exposure time, feeding features, tea consumption and body mass index; the age, sex, smoking and alcohol con¬sumption were not statistically significant. Conclusion: Ultraviolet and light skin colours are important etiological factors in the development of BCC. The effects of nutrition and tea consumption may be researched by detailed studies on the development of BCC.
Abstract (Original Language): 
Amaç: Bu çalışmada klinik ve histopatolojik olarak bazal hücreli karsinom (BHK) tanısı alan hastalarda ety-olojide rolü olabileceği düşünülen faktörlerin araştırılmasını amaçladık. Materyal ve metod: Çalışmamızda 58 BHK'lı hasta ile 45 kontrol olgusunda BHK gelişiminde rol oynayabileceği düşünülen çevresel etkenler ve yaşam tarzları araştırılmıştır. Bulgular : İki grup arasında, deri tipi, güneşte kalma süresi, beslenme özellikleri, çay içimi ve vücut kitle indeksi açısından istatistiksel olarak anlamlı fark bulunurken; yaş, cinsiyet, sigara içimi ve alkol kullanımı açısından istatistiksel olarak anlamlı fark bulunamadı. Sonuç: BHK gelişmesinde ultraviyole ve açık renk deri tipine sahip olmak önemli bir etyolojik faktördür. Beslenme ve özellikle de çay tüketiminin, BHK gelişimi üzerine olan etkisinin kapsamlı çalışmalarla araştırıl¬ması gereklidir.
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REFERENCES

References: 

1. Stern RS. The mysterles of geographic variability in nonmelanoma skin cancer incidence. Arch Dermatol 1999;135:843-4.
2. Ratner D, Peacocke M, Zhang H, Ping XL, Tsou HC. UV-specific p53 and PTCH mutations in sporadic basal cell carcinoma of sun-exposed skin. J Am
Acad Dermatol 2001;44:293-7.
3. Odom RB, James WD, Berger TG. Andrews' Diseases of the Skin. Philadelphia: W.B Saunders
Company. 2000;820-9.
4. Lu YP, Lou YR, Li XH, Xie JG, Brash D, Huang MT, Conney AH. Stimulatory effect of oral adminis¬tration of green tea or caffeine on ultraviolet light-induced increases in epidermal wild-type p53, p21(WAF1/CIP1), and apoptotic sunburn cell in SKH-1 mice. Cancer Res 2000;60:4785-91.
5.
Erde
m T, Parlak M, Aktaş A, Koy S, Gündoğdu C. Bazal hücreli epitelyomanın klinik ve histopatolojik değerlendirilmesi. Türk J Dermatopathol 1996;3-4:143-8.
6. Sahl WJ, Glore S, Garrison P, Oakleaf K, Johnson SD. Basal cell carcinoma and life style characteristics.
Int J Dermatol 1995;34:398-402.
7. Kune GA, Bannerman S, Field B, Watson LF, Cleland H, Merenstein D, Vitetta L. Diet, alcohol, smoking, serum beta-carotene and vitamin A in male nonmelanocytic skin cancer patients and controls. Nutr Cancer 1992;18:237-44.
8. Black HS, Lenger WA, Gerguis J, Thornby JI. Relation of antioxidants and level of dietary lipid to epidermal lipid peroxidation and ultraviolet carcino-genesis. Cancer Res 1985;45:6254-9.
9. Rosso S, Jaris F, Zanetti R. Risk of basal and squa-mous cell carcinomas of the skin in Sion, Switzerland: A case control study. Tumori
1999;85:435-42.
10. Betti K, Inselvini E, Carducci M, Crosti C. Age and site prevalence of histologic subtypes of basal cell carcinomas. Int J Dermatol 1995;34:174-6.
11. Hannuksela-Svahn A, Pukkala E, Karvonen J. Basal cell skin carcinoma and other nonmelanoma
Süleyan
eire
l niversitesi Tıp Fa
skin cancer in Filland from 1956 through 1995. Arch Dermatol 1999;135:781-6.
12. Lenk N,
All
ı N, Bilen F. 1987-1993 yılları arasın¬da Ankara Numune Hastanesi Dermatoloji Kliniğine başvuran deri tümörlü olguların değerlendirilmesi. Türkderm 1996;30:21-4.
13. Leffell DJ, Fitzgerald DA. Basal Cell Carcinoma. In: Freedberg IM, Eisen AZ, Wolff K, Austen KF, Goldsmith LA, Katz SI, Fitzpatrick TB eds. Dermatology in General Medicine, 5th ed. NewYork:
Mc Graw Hill Company, 1999;857-64.
14. Naldi L, DiLandro A, D'Avanzo B, Parazzini F. Host-related and environmental risk factors for cuta¬neous basal cell carcinoma: Evidence from an Italian case-control study. J Am Acad Dermatol
2000;42:446-52.
15. Koh HK, Bhawan J. Tumors of the Skin. In Moschella SL, Hurley HJ eds. Dermatology, 3th ed. Philadelphia: WB Saunders Company, 1992;1721-
808.
16. Coebergh JWW, Neumann HAM, Vrints LW, Heiden LVD, Heier WJ, Teulings V. Trends in the incidence of non-melanoma skin cancer in the SE Netherlands 1975-1988: A registry-based study. Br J
Dermatol 1991;125:353-9.
17. Stem RS, Weinstein MC, Baker SG. Risk reduc¬tion for nonmelanoma skin cancer with childhood sunscreen use. Arch Dermatol 1986;122:537-45.
18. Kaskinen A, Oikarinen A. Nonmelanoma skin cancer in Northern Finland. Int J Dermatol
1996;35:700-3.
19. Czarnecki D, Meehan C, O'Brien T, Leahy S,
Nash C. The changing face of skin cancer in Australia. Int J Dermatol 1991;30:715-7.
20. Gallagher RP, Hill GB, Dajdik CO, Fincham S, Coldman AJ, McLean DI, Threlfall WJ. Sunlight
exposure pigmentary factors and risk of non-melanocytic skin cancer. Arch Dermatol
1995;131:157-63.
21. Merimsky O, Inbar M. Cigarette smoking and skin cancer. Clinics in Dermatology 1998;16:585-8.
22. Begg CB. The search for cancer risk factors: When can we stop looking? Am J Public Health 2001;91:360-4.
23. Katiyar SK, Ahmad N, Mukhtar H. Green tea and skin. Arch Dermatol 2000;136:989-94.
24. Trevisanato SI, Kim YI. Tea and health. Nutrition Reviews 2000;58:1-10.

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