Buradasınız

Böbrek Toplayıcı Tübül Kanseri: Olgu Sunumu

Renal Collecting Duct Carcinoma: A Case Report

Journal Name:

Publication Year:

Abstract (2. Language): 
Collecting duct carcinomas are seen extremely rare. In this report, a 9 years old girl, who admitted to our clinic with hematuria and left flank pain for three months, is presented. Abdominal ultrasonography (USG), computed tomography (CT) and magnetic resonance (MRI) revealed a lobulated, hypoechoic, solid mass lesion The mass was 3x2.5 cm in diameters and located at the left renal pelvis level. Left transperitoneal radical nephrectomy was performed. The histopathological diagnosis was collecting duct carcinoma (Bellini) of papillary tubular type. Immunohistochemically, neoplastic cells had positive immunoreactivity to cytokeratine-7 (CK-7), HMWCK and CEA. Reevaluation of the patient, other organs involvement and local recurrence was not detected. Collecting duct carcinomas (CDC) are seen extremely rare and have poor prognosis and their diagnosis are difficult.
Abstract (Original Language): 
Renal hücrel i karsinomlar içerisinde toplayıcı duktal karsinomlar son derece nadir görülür. Bu çalışmada son üç aydır var olan sol yan ağrısı ve pıhtılı hematim şikâyetiyle başvuran 9 yaşında kız çocuğu sunulmuştur. Abdominal utrasonografi (USG), bilgisayarlı tomografi (BT), manyetik rezonans (MRI)' da sol böbrek renal pelvis düzeyinde 3 x 2,5 cm boyutda solid kitle lezyonu tespit edildi. Hastaya sol transperitoneal radikal nefrektomi uygulandı. Histopatolojik değerlendirmede; toplayıcı duktal karsinomun papiller tubüler tipi olarak rapor edildi. İmmünhistokimyasal incelemede; sitokeratin-7 (CK-7), HMWCK ve CEA ile immünreaktivite belirlendi. Hastanın kontrollerinde başka organ yayılımı ve lokal nüks saptanmadı. Toplayıcı duktal karsinomlar, son derece ender ve tanısı zor konulan tümörlerdir ve prognozu oldukça kötü seyretmektedir.
212-214

REFERENCES

References: 

1. Kovacs G, Akhtar M, Beckwith BJ, et al. The Heidelberg Classification of renal tumors. J Path 1997; 183: 131-135.
2. Antonelli A, Portesi E, Cozzoli A, et al. The collecting duct carcinoma of the kidney: A cytogenetical study. Eur Urol
2003; 43: 680-685.
3. Kirkali Z, Çelebi I, Akan G, Yörükoğlu K. Bellini duct (collecting duct) carcinoma of the kidney. Urology 1996; 47:
921-923.
4. Gregori-Romero MA, Morell-Quadreny L, Llombart- Bosch A. Cytogenetic analysis of three primary Bellini duct carcinomas. Genes Chromosomes Cancer 1996; 15: 170-172.
5. Mejean A, Roupret M, Larousserie F, Hopirtean V, Thiounn N, Dufour B. Is there a place for radical nephrectomy in the presence of metastatic collecting duct (bellini) carcinoma? J Urol 2003; 169: 1287-1290.
213
Fırat Tıp Dergisi
2011
; 16(4): 212-214
6. Castellino SM, McLean TW. Pediatric genitourinary tumors.
Curr Opin Oncol 2007; 19: 249-253.
7. Weeks DA, Mierau GW. Renal Tumors of Childhood: A
Pragmatic Approach. Pathology Case Reviews 2006; 11: 156¬160.
8. Olivere JW, Cina SJ, Rastogi P, RO YJ. Collecting duct
meningeal carcinomatosis. Arch Pathol Lab Med 1999; 123:
638-641.
9. Diven SC, Travis LB. A practical primary care approach to hematuria in children. Pediatr Nephrol 2000; 14: 65-72.
10. Carter MD, Tha S, McLoughlin MG, Owen OA. Collecting
duct carcinoma of the kidney: A case report and review of the
literature. J Urol 1992; 147: 1096-1098.
11. Lack EE, Cassady JR, Sallan SE. Renal cell carcinoma in childhood and adolescence. A clinical and pathological study
of 17 cases. J Urol 1985; 133: 822-828.
Oğuz ve Ark.
12. Fleming S, Lewi HJE. Collecting carcinoma of the kidney.
Histopathology 1986; 10: 1131-1141.
13. Kennedy SM, Merino MJ, Linehan WM, Roberts JR, Robertson CN, Neumann RD. Collecting duct carcinoma of
the kidney. Hum Pathol 1990; 21: 449-456.
14. Srigley JR, Eble JN. Collecting duct carcinoma of kidney.
Semin Diagn Pathol 1998; 15: 54-67.
15. Hart AP, Brown R, Lechago J, Truong LD. Collision of transitional cell carcinoma and renal cell carcinoma. An immunohistochemical study and review of the literature.
Cancer 1994; 73: 154-159.
16. Dimopoulos MA, Logothetis CJ, Markovitz A, Sella A, Amato R, Ro J. Collecting duct carcinoma of the kidney. Br J Urol
1993; 71: 388-391.

Thank you for copying data from http://www.arastirmax.com