Buradasınız

Anasayfa » Content

Rekürren üriner sistem enfeksiyonları

Recurrent urinary tract infections

Journal Name:

  • Gülhane Tıp Dergisi

Publication Year:

  • 2008

Key Words:

Keywords (Original Language):

Author Name
Abstract (2. Language): 
Urinary tract infections are one of the most common bacterial infections in especially women, and approximately one forth of these show a recurrence. Most of these infections do not have any complications. Several factors are suggested responsible for the recurrence of urinary tract infections. Of these, there are sexual intercourse, use of contraceptives, antimicrobials and oestrogen, genetic factors, and the short distance between the anus and urethra. Escherichia coli is the most common microorganism causing urinary tract infections. A variety of choices are present in the treatment. Long-term treatment, prophylaxis after intercourse, treatment initiated by the patient, and prophylactic estrogen and cranberry juice use are examples of treatment modalities. Use of vaccines and hyaluronic acid are currently under investigation.
Bookmark/Search this post with
Abstract (Original Language): 
Üriner sistem enfeksiyonları özellikle kadınlarda en sık görülen bakteriyel enfeksiyonlardandır ve yaklaşık dörtte birinde tekrarlayıcı karakterdedir. Bu enfeksiyonların büyük çoğunluğu komplikasyon oluşturmaz. Bir çok faktör, üriner sistem enfeksiyonlarının tekrarından sorumlu tutulmuştur. Bunlar arasında; cinsel aktiviteler, kontraseptif kullanımı, antimikrobiyal kullanımı, östrojen, genetik faktörler ve anüs ile üretra arasındaki mesafenin kısalığını sayabiliriz. Bu enfeksiyonlardan en yaygın olarak Escherichia coli bakterileri sorumlu tutulur. Tedavide değişik seçenekler uygulanmaktadır. Uzun süreli tedavi veya cinsel temas sonrası profilaksi ve hastanın kendiliğinden baş- ladığı tedavi, profilaktik olarak östrojen ve yabanmersini suyu kullanılması gibi seçenekler bu kapsamda sayılabilir. Aşı seçenekleri ve hyaluronik asid kullanımı halen araştırılmaktadır.
FULL TEXT (PDF): 
PDF icon arastirmax-rekurren-uriner-sistem-enfeksiyonlari.pdf
  • 3
226-231
  • Turkish

REFERENCES

References: 

Kaynaklar
1. Franco AVM. Recurrent urinary tract infections. Best
Pract Res Clin Obstetr Gynecol 2005; 19: 861-873.
2. Sobel JD, Kaye D. Urinary tract infection. In: Mandell
GL, Bennett JE, Dolin R (eds). Principles and Practice
of Infectious Diseases. 4th ed. New York: Churchill
Livingstone, 1995: 662-690.
3. Ünal S, Akalın H. Üriner sistem infeksiyonları. In: Kanra
G, Akalın E. İnfeksiyon Hastalıkları. 2nci baskı. Ankara:
Güneş Kitabevi, 1993: 167-189.
4. Kunin CM. Urinary tract infections in females. Clin
Infect Dis 1994; 18: 1-12.
5. Stamm WE, Raz R. Factors contributing to susceptibility
of postmenopausal women to recurrent urinary tract
infection. Clin Infect Dis 1999; 28: 723-725.
6. Hooton TM, Stamm WE. Diagnosis and treatment of
uncomplicated urinary tract infection. Infect Dis Clin
North Am 1997; 11: 551-581.
7. Foxman B, Marsh J, Gillespie B, Rubin N, Koopman
JS, Spear S. Condom use and first-time urinary tract
infection. Epidemiology 1997; 8: 637-641.
8. Scholes D, Hooton TM, Roberts PL, Stapleton AE, Gupta
K, Stamm WE. Risk factors for recurrent UTI in young
women. J Infect Dis 2000; 182: 1177-1182.
9. Stamm WE. Aproach to the patient with urinary tract
infection. In: Gorbach SL, Barlett JG, Blacklow NR
(eds). Infectious Diseases. Philedelphia: WB Saunders
Company, 1992: 788-798.
10. Meares EM. Current patterns in nosocomial urinary
tract infections. Urology 1991; 37: 9-12.
11. Özsüt H, Çalangu S. İdrar yolu infeksiyonları. In: Willke
Topçu A, Söyletir G, Doğanay M (eds). İnfeksiyon
Hastalıkları. İstanbul: Nobel Tıp Kitabevi, 1996:
921-926.
12. Hooton TM, Stamm WE. The vajinal flora and UTIs.
In: Mobley HLT, Warren JW (eds). UTIs: Molecular
Pathogenesis and Clinical Management. Washington,
DC: ASM Press, 1996: 67-94.
13. Hooton TM, Winter C, Tiu F, Stamm WE. Association
of acute cystitis with the state of the menstrual cycle in
young women. Clin Infect Dis 1996; 23: 635-636.
14. Raz R, Stamm WE. A controlled trial of intravaginal
pestriol in postmenopausal women with recurrent
urinary tract infections. N Engl J Med 1993; 329:
753-756.
15. Robinson D, Cardozo L. Oestrogen and the lower
urinary tract. BJOG 2004; 111: 10-14.
16. Gupta K, Stamm WE. Pathogenesis and management
of reccurent urinary tract infections in women. World J
Urol 1999; 17: 415-420.
17. Ishıtoya S, Yamamoto S, Mitsumori K, Ogawa O, Terai
A. Non-secretor status is associated with female acute
uncomplicated pyelonephritis. BJU Int 2002; 89:
851-854.
18. Lomberg H, Cedergren B, Leffler H, Nilsson B, Carlström
AS, Svanborg-Edén C. Influence of blood group on the
availability of receptors for attachment of uropathogenic
Escherchia coli. Infect Immun 1986; 51: 919-926.
19. Remis RS, Gurwith MJ, Gurwith D, et al. Risk factors
for urinary tract infection. Am J Epidemiol 1987; 126:
685-694.Cilt 50 • Sayı 3 Rekürren üriner sistem enfeksiyonları • 231
20. Strom BL, Collins M, West SL, et al. Sexual activity,
contraceptive use, and other risk factors for symptomatic
and asymptomatic bacteriuria. Ann Int Med 1987; 107:
816-823.
21. Foxman B, Chi JW. Health behaviour and urinary tract
infections in college-aged women. J Clin Epidemiol
1990; 43: 329-337.
22. Stamm WE, Hooton TM. Management of urinary
tract infections in adults. N Engl J Med 1993; 329:
1328-1334.
23. Ronald AR, Harding GKM. Complicated urinary
tract infections. Infect Dis Clin North Am 1997; 11:
583-592.
24. Russo TA, Stapleton A, Wendercth S, et al. Chromosomal
restriction fragment length polymorphism analysis of
Escherichia coli strains causing recurrent urinary tract
infections in young women. Infect Dis J 1995; 172:
440-445.
25. Stapleton A, Stam WE. Prevention of urinary tract
infection. Infect Dis Clin North Am 1997; 11: 719-733.
26. Sobel JD. Pathogenesis of urinary tract infection. Role
of host defenses. Infect Dis Clin North Am 1997; 11:
531-549.
27. Johnson JR. Microbial virulence determinants and the
pathogenesis of urinary tract infection. Infect Dis Clin
North Am 2003; 17: 261-278.
28. Mulvey MA. Adhesion and entry of uropathogenic
Escherichia coli. Cell Microbiol 2002; 4: 257-271.
29. Hultgren SJ, Araham S, Caparon M, et al. Pilus and
nonpilus bacterial adhesions; assembly and function in
cell recognition. Cell 1993; 73: 887-901.
30. Dodson KW, Pinkner JS, Rose T, et al. Structural basis of
the pyelonephritic E. coli adhesion to its human kidney
receptor. Cell 2001; 105: 733-743.
31. Stamm WE, Counts GW, Running KR, et al. Diagnosis
of coliform infection in acutely dysuric women. N Engl
J Med 1982; 307: 463-468.
32. Stewens M. Screening urines for bacteriuria. Med Lab
Science 1989; 46: 194-206.
33. Van Haarst EP, Van Andel G, Heldeweg EA, Schlatmanna
TJM, Van der Horstc HJR. Evaluation of the diagnostic
work up in young women referred for recurrent lower
urinary tract infections. Urology 2001; 57: 1068-1072.
34. Nicolle LE. Urinary tract infection: traditional
pharmacologic therapies. Am J Med 2002; 113: 35–44.
35. Albert X, Huertas I, Pereiró I, Sanfélix J, Gosalbes V,
Perrota C. Antibiotics for preventing recurrent urinary
tract infection in non pregnant women. Cochrane
Database Syst Rev 2004; 3: CD001209.
36. Schaeffer AJ, Jones JM, Flynn SS. Prophylactic efficacy of
cinoxacin in recurrent urinary tract infection: biologic
effect on the vaginal and fecal flora. J Urol 1982; 127:
1128-1131.
37. Esposito G. Estriol: a weak estrogen or a different
hormone? Gynecol Endocrinol 1991; 5: 131-153.
38. Leiner S. Recurrent urinary tract infections in otherwise
healthy adult women. Rational strategies for work-up
and management. Nurse Pract 1995; 20: 48-56.
39. Hooton TM. Reccurent urinary tract infection in
women. Int J Antimicrob Agents 2001; 17: 259-268.
40. Avorn J, Monane M, Gurwitz J, Glynn RJ, Choodnovskiy
I, Lipsitz LA. Reduction of bacteriuria and pyuria after
ingestion of cranberry juice. JAMA 1994; 271: 751-754.
41. Patel N, Daniels I. Botanical perspectives on health
of cystitis and cranberries. J R Soc Health 2000; 120:
52-53.
42. Thankavel K, Madison B, Ikeda T, et al. Localization of
a domain in the FimH adhesin of Escherichia coli type
1 fimbriae capable of receptor recognition and use of a
domain-specific antibody to confer protection against
experimental urinary tract infection. J Clin Invest 1997;
100: 1123-1136.
43. Constantinides C, Manousakas T, Nikolopoulos
P, Stanitsas A, Haritopoulos K, Giannopoulos A.
Preventions of recurrent bacterial cystitis by intravesical
administration of hyaluronic acid: a pilot study. BJU Int
2004; 93: 1262-1266.
44. Lipovac M, Kurz C, Reithmayr F, Verhoeven HC, Huber
JC, Imhof M. Prevention of recurrent bacterial urinary
tract infections by intravesical instillation of hyaluronic
acid. Int J Gynaecol Obstet 2007; 96: 192-195.
45. Hopkins WJ, Elkahwaji J, Beierle LM, Leverson GE,
Uehling DT. Vaginal mucosal vaccine for recurrent
urinary tract infections in women: results of a phase 2
clinical trial. J Urol 2007; 177: 1349-1353.

Thank you for copying data from http://www.arastirmax.com