Buradasınız

Sınırlı bir Wegener granülomatozis olgusu

A case of Wegener’s granulomatosis with limited involvement

Journal Name:

Publication Year:

Abstract (2. Language): 
Wegener’s granulomatosis is an autoimmune, idiopathic disease, characterized by granulomatous vasculitis which involves small arteries and veins in any organ of the body. The disease has limited and systemic forms. It may manifest with symptoms of ear and nose. Otolaryngologists should have a great care and awareness since the diagnostic delay is most often seen in patients presenting with head and neck symptoms. We herein present a case of Wegener’s granulomatosis with prominent involvement of ear and nose in the light of related articles.
Abstract (Original Language): 
Wegener granülomatozisi, vücudun herhangi bir organını etkileyebilen, kü- çük arter ve venleri tutan, granülomatöz vaskülit ile karakterize, otoimmün, idiyopatik bir hastalıktır. Sınırlı ve sistemik formları vardır. Kulak ve burun semptomları ile kendini gösterebilir. Tanıda en fazla gecikme baş ve boyun bölgesi ile ilgili semptomlarla başvuran hastalarda olduğu için, kulak burun boğaz hekimlerinin bu konuda büyük bir dikkate ve farkındalığa ihtiyaçları vardır. Yazımızda kulak ve burun tutulumu ön planda olan sınırlı bir Wegener granülomatozis olgusunu ilgili literatürler ışığında sunduk.
298-301

REFERENCES

References: 

Kaynaklar
1. Jennette JC, Falk RJ, Andrassy K, et al. Nomenclature
of systemic vasculitides. Proposal of an International
Consensus Conference. Arthritis Rheum 1994; 37:
187-192.
2. Banerjee A, Armas JM, Dempster JH. Wegener’s
granulomatosis: diagnostic dilemma. J Laryngol Otol
2001; 115: 46-47.
3. Chegar BE, Kelley RT. Wegener’s granulomatosis
presenting as unilateral parotid enlargement.
Laryngoscope 2004; 114: 1730-1733.
4. Macias JD, Wackym PA, McCabe BF. Early diagnosis of
otologic Wegener’s granulomatosis using the serologic
marker C-ANCA. Ann Otol Rhinol Laryngol 1993; 102:
337-341.
5. Boudes P. Purely granulomatous Wegener’s
granulomatosis: a new concept for an old disease.
Semin Arthritis Rheum 1990; 19: 365-370.
6. Rinaldo A, Sacilotto C, Mannara GM, Florio F, Ferlito
A. Wegener’s granulomatosis presenting with otologic
manifestations. J Otolaryngol 1999; 28: 347-350.
7. Gubbels SP, Barkhuizen A, Hwang PH. Head and
neck manifestations of Wegener’s granulomatosis.
Otolaryngol Clin North Am 2003; 36: 685-705.
8. Srouji IA, Andrews P, Edwards C, Lung WJ. Patterns of
presentation and diagnosis of patients with Wegener’s
granulomatosis: ENT aspects. J Laryngol Otol 2007;
121: 653-658.
9. McDonalds TJ, DeRemee RA. Wegener’s granulomatosis.
Laryngoscope 1983; 93: 220-231.
10. Takagi D, Nakamaru Y, Maguchi S, Futura Y, Fukuda S.
Otologic manifestations of Wegener’s granulomatosis.
Laryngoscope 2002; 112: 1684-1690.
11. Knight JM, Hayduk MJ, Summerlin DJ, Mirowski GW.
Strawberry gingival hyperplasia: a pathognomonic
mucocutaneous finding in Wegener granulomatosis.
Arch Dermatol 2000; 136: 171-173.
12. Lloyd G, Lund VJ, Beale T, Howard D. Rhinologic
changes in Wegener’s granulomatosis. J Laryngol Otol
2002; 116: 565-569.
13. Leavitt RY, Fauci AS, Bloch DA, et al. The American
Collage of Rheumatology 1990 criteria for the
classification of Wegener’s granulomatosis. Arthritis
Rheum 1990; 33: 1101-1107.
14. Macias JD, Wackym PA, McCabe BF. Early diagnosis of
otologic Wegener’s granulomatosis using the serologic
marker C-ANCA. Ann Otol Rhinol Laryngol 1993; 102:
337-341.
15. Nölle B, Specks U, Lüdemann J, Rohrbach MS, DeRemee
RA, Gross WL. Anticytoplasmatic autoantibodies: their
immunodiagnostic value in Wegener’s granulomatosis.
Ann Intern Med 1989; 111: 28-40.
16. Denavey KO, Travis WD, Hoffman G, Leavitt R, Lebovics
R, Fauci AS. Interpretation of head and neck biopsies
in Wegener’s granulomatosis. A pathologic study of
126 biopsies in 70 patients. Am J Surg Pathol 1990; 14:
555-564.
17. Fenton JE, O’Sullivan TJ. The otological manifestations
of Wegener’s granulomatosis. J Laryngol Otol 1994;
108: 144-146.
18. Moussa AE, Abou-Elhmd KA. Wegener’s granulomatosis
presenting as mastoiditis. Ann Otol Rhinol Laryngol
1998; 107: 560-563

Thank you for copying data from http://www.arastirmax.com