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Gastric malignancy presenting as extensive osteolytic lesions

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Abstract (2. Language): 
Gastric malignancy presenting as low backache due to bone metastasis from the primary is rare. We report a case of 51 year old male presented with low back ache from extensive metastases to the spine, which on evaluation originated from adenocarcinoma of the stomach. Magnetic resonance imaging of the spine showed osteolytic metastases in vertebral body in the whole of the spine and pelvic girdle. Gastrointestinal endoscopy revealed ulcerative growth in the stomach that on biopsy showed poorly differentiated adenocarcinoma. This case is reported since the initial presentation of gastric cancer was bony metastases without any features of primary malignancy which causes diagnostic dilemma.
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REFERENCES

References: 

1. Ahn JB, Ha TK, Kwon SJ. Bone metastasis in gastric cancer patients. J Gastric Cancer. 2011; 11:38–45.
2. Nottebaert M, Exner GU, von Hochstetter AR, Schreiber A. Metastatic bone disease from occult
carcinoma: a profile. Int Orthop. 1989;13:119–23.
3. Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D. Global cancer
statistics. CA Cancer J Clin 2011; 61: 69–90.
4. Mohandas KM, Swaroop VS, Krishnamurthy S, Desai DC,Dhir V, Pradhan SA,et al . Unusual bone
metastasis as the initial symptom of gastric cancer--a reportof four cases. Indian J Cancer. 1993; 30:146-50.
5. Kusumoto H, Haraguchi M, Nozuka Y, Oda Y, Tsuneyoshi M, Iguchi H. Characteristic features of
disseminated carcinomatosis of the bone marrow due to gastric cancer:the pathogenesis of bone
destruction. Oncol Rep.2006;16:735–740.
6. Sagara K, Fujiyama S, Kin F, Sato T. An unusual case of Gastric carcinoma initially presenting bone
metastasis and later transverse myelopaty. Jpn J Clin Oncol. 1985 ; 15:133-4.
Indian Journal of Basic and Applied Medical Research; March 2015: Vol.-4, Issue- 2, P. 385-388
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www.ijbamr.com P ISSN: 2250-284X , E ISSN : 2250-2858
7. Kamiyo T, Honda K, Kizaki M, Maruyama T, Masuda T, Suzuki O, et al. Clinicopathological studies on
disseminated carcinomatosis of the bone marrow occurring through metastasis of gastric carcinoma. Gan
No Rinsho. 1985;31: 819-26.

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