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Retroperitoneal Malign Tümöre Benzeyen, Stromadan Zengin Varyant Castleman Hastalığı: Olgu Sunumu

Stroma-Rich Variant of Castleman Disease Mimicking Retroperitoneal Malign Tumor: Case Report

Journal Name:

  • İnönü Üniversitesi Tıp Fakültesi Dergisi

Publication Year:

  • 2009

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
Castleman’s Disease is a rare entity which is characterized by the benign proliferation of lymphoid tissue. Generally it is asymptomatic and seen in young adults. Mostly it is located in mediastinum but it can also be seen at neck, axillary, intraabdominal and retroperitoneal locations. Most of the retroperitoneal masses are malignant. Because of difficulty in differentiate benign Castleman’s Disease from malign tumors clinically and radiologically, Castleman’s Disease should be remembered in differential diagnosis of retroperitoneal masses. The stroma rich variant is a new subtype of Castleman’s disease and its morphoimmunophenotypical characteristics make it necessary to be differentiated from spindle cell tumors. A 45 years old woman with stromal rich variant hyaline vascular type of Castleman’s Disease with retroperitoneal location is reported due to its rare presence in this localization and possibility of interference with malignant disease.
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Abstract (Original Language): 
Castleman hastalığı, lenfoid dokunun benign proliferasyonu ile karakterize, nadir görülen bir hastalıktır. Genellikle genç erişkinlerde görülür ve asemptomatik seyreder. Hastalığın en yaygın yerleşimi mediasten olsa da retroperiton, boyun, aksilla ve batında da görülebilir. Retroperiton yerleşimli kitlelerin çoğu maligndir. Klinik ve radyolojik olarak Castleman hastalığının malign tümörlerden ayırıcı tanısının zor olması nedeniyle retroperitoneal kitlesi olan olgularda akla gelmelidir. Stromadan zengin varyant, Castleman hastalığının yeni tanımlanan bir alt grubu olup zaman zaman morfoimmunofenotipik özellikleri iğsi hücreli tümörlerden ayırıcı tanısının yapılmasını gerektirmektedir. 45 yaşında retroperitoneal yerleşimli stromadan zengin varyant hyalen vasküler tip Castleman hastalığı olgusu, bu lokalizasyonda az görülmesi ve malign hastalıklarla karışması nedeniyle sunulmuştur.
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  • 1
41-43
  • Turkish

REFERENCES

References: 

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