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ANTIOXIDANT POTENTIAL OF CINNAMALDEHYDE; AN INVITRO STUDY

Journal Name:

  • The International Journal of Pharmaceutical Research and Bio-Science

Publication Year:

  • 2013

Key Words:

Author Name
Abstract (2. Language): 
Antioxidants are the agents that are capable of effectively neutralizing the deleterious effects of free radicals. Therefore, the need for the search of antioxidants from natural origin has been greatly felt in the recent years. Cinnamaldehyde (CA) exert antimicrobial, anti tumor, anti inflammatory, anti diabetic effects as well as anti gastric properties. CA is potential against different free radicals which result in oxidative damage leading to various diseases. Current work was carried to evaluate the radical scavenging activities using different invitro models like DPPH, Superoxide, Nitric Oxide, H2O2 scavenging activity and Reducing power. Total antioxidant capacity expressed as equivalents of 160μg of Vitamin E / g of CA. CA has shown potent antioxidant activity in these methods with IC50 values of 377, 391, 437, 390 and 462μg/ml, respectively. The antioxidant activity of CA was compared with the standards like Ascorbic acid (AA) and Butylated hydroxy toluene (BHT). The results obtained in the present study indicate that the CA can act as a potential source of antioxidant scavenging free radicals and preventing oxidative stress leading to various diseases.
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