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0-2 YAŞ ARASI ÇOCUKLARDA SAÇ KURŞUN DÜZEYLERİ VE KRONİK KURŞUNA MARUZ KALMA NEDENLERİ

Journal Name:

  • İstanbul Tıp Fakültesi Dergisi

Publication Year:

  • 2003

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
SUMMARY llair lead levels in children under the age of 2 years and factors determining ehronic lead exposwe. The aim of this study was to determine hair lead levels and the risk factors of lead poisoning among infants under 2 years of age in istanbul. Lead poisoning in children results from the ingestion of lead in the environ-ment ineluding paint chips, dust, soil, drinking water, consumer produets, enamel utensüs and traditional medicines and usually oecur between the second and third year of life. Lead İs normally present in the hair of healthy subjects, but its concentration varies widely depending on diet and environment. The levels of lead İn hair reflect a long term or past exposure averaging their extent during the perİod of theİr growth. Since hair is readily available and easy to obtain, hair lead nıeasurements may provide a simple tool for sereening. Using a longitudinal design in this study, we obtaincd repeated measures of hair lead levels. A questionnaire was applied to each care giver to identify risk factors for lead exposure. This study was con-dueted at the " Well-Cİıild Unit" based in the istanbul Faculty of Medicine. The families of 199 infants ga-ve their consent for this study. Written consent was obtaİned from care givers of the children. Inclusion criteria for the study were as follows: an uneventfui pregnaney; healthy term infants; birth weight of at ie-ast 2500 g wİth no apparent congenital defeets. Hair samples were colleeted when the infants were aged 1, 6, 12 and 24 months. Ali samples were assessed using atomic absorption speclrophotometer (Varian speetra AA 200, GTA-100). There were 199 infants at the beginning of the study. 193 were left at 6 months, 185 at 12 months and at the end of the study there were İ3I remaining. Hair lead levels inerea-sed by age. Hair lead levels were 2+ 1.6 İn the fİrst month, 3.4+3.0 at 6. month, 4.3+ 3.8 at 12. month, 5.3+ 3.4ug/g at 24. months of age. There were statistically significant dfferences between months (p<0.001). Children who were given herbal teas and who were exposed to smoking environment, and li-ved İn centrally heated homes, and whose fathers were manual workers had significantly high hair lead levels. Our findings suggest that hair lead levels may be a useful parameter to show ehronic lead exposurc and al-so our findings carry some messages for public health nıeasurements such as the nced for avoiding the use of herbal teas and, avoiding passive smoking for the sake of children less than two years of age. Parents and parents-to-be should perhaps take note of these findings in order to gİve their children a healthy start İn life.
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Abstract (Original Language): 
Araştırmamızın amacı 2 yaşından küçük sağlıklı çocuklar arasında saç kurşun düzeylerini ölçmek ve çocukların kronik kurşunla karşılaşma nedenlerini saptamaktır. Kurşun normalde saçta bulunmaktadır. Beslenme, çevresel şartlar nedeniyle miktarı değişebilir. Saçtaki kurşun konsantrasyonu uzun süreli kurşuna maruz kalmanın bir göstergesidir. Saç kolaylıkla uzayıp ve kolayca çocuklardan kolaylıkla alınabileceği için uzun süreli kurşuna maruz kalma ile ilgili toplumsal çalışmalarda veri olarak kullanılabilir. Çalışma prospektif yöntemle İstanbul Tıp Fakültesi Çocuk Sağlığı vc Hastalıkları Ana Bilim Dalı Sağlam Çocuk Polikliniğine Mart 1998 ile Eylül 2000 yıllan arasında başvuran çocuklar arasından yürütüldü. Olgular doğum tartısı 2500g üzerinde, miyadında doğmuş, kronik bir hastalığı olmayan, ailesi bir yıkhr İstanbul'da aynı adreste oturan çocuklardı. Bu çocukların ailelerine sosyo-ekonomik, demografik ve çocukların beslenme bilgilerini almak için 18 soruluk anket uygulandı. İlk başvuran 199, ö.ayda 193, 12 ayda 185, 24 ayda 131, çocuktan alman saç örneklerinde kurşun düzeyleri Atomik Absorbsiyon Spektrofotometresinin Grafit Fırın Ünitesinde (Varİan speetra AA 200, GTA-100) çalışılarak değerlendirildi.. Saç kurşun düzeyinin yaşla birlikte arttığı saptandı. Saç kurşun düzeyleri 1 ay 2± 1.6, 6. ay 3.4+3.00, 12. ay 4.3± 3.8, 24 ay 5.3± 3.4ug/gr İdi. Bu fark istatistiksel açıdan anlamlı idi (p<0.001). Bitkisel çay verilen (ıhlamur, rezene, anason, nane vb), sigara dumanına maruz kalan, kaloriferli evlerde yaşayan çocukların saç kurşun düzeyi yüksek bulundu. Baba mesleğine göre saç kurşun düzeyinde farklılıkların olduğu saptandı.
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  • Turkish

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