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EPİDERMAL BÜYÜME FAKTÖRÜ RESEPTÖRÜNÜN (EGFR) AĞIZ BOŞLUĞUNDA GÖRÜLEN EPİDERMOİD KARSİNOM VE ODONTOJEN KİST EPİTELİNDE İMMUNOHİSTOKİMYASAL YÖNTEMLE ARAŞTIRILMASI

AN IMMUNOHISTOCHEMICAL INVESTIGATION OF EPİDERMAL GROWTH FACTOR RECEPTOR (EGFR) EXPRESSION IN ODONTOGENIC CYST EPITHELIUM AND EPIDERMOID CARCINOMA OF ORAL CAVITY.

Journal Name:

  • İstanbul Üniversitesi Diş Hekimliği Fakültesi Dergisi

Publication Year:

  • 1997

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
In this research, the patients who were applied to dental Faculty of İstanbul University, Department of Oral Surgery were evaluated and 40 cases who were diagnosed as epidermoid carcinoma, heratocyst, follicular and radicular cysts following the clinical, radiological andpaOtological examination were histochemicalty investigated according to the presence of Epidermal Growth Factor Receptor (EGFR). The EGFR presence was observed in epidermoid carcinoma and keratocyst (% 90), follicular ( % 60), radicular (% 50) cysts respectively. Based on the above results, we would like to emphasize that EGFR has a characteristic of epithelial malignancy.
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Abstract (Original Language): 
Bu çalışmada, İ.Ü. Diştıekimliği Fakültesi, Âğız Diş. Çene Hastalıkları ve Cerrahisi Anabilitn Dalı'na başvuran ve yapılan klinik, radyolojik ve patolojik incelemeleri sonucu epidermoid karsinonı, keratokist, folikü-ler kist, ve radiküler kist tanısı konulan toplam 40 olgu immunohistokimyasal yöntem ile çalışılarak Epidermal Büyüme Faktörü Reseptörü (EGFR) varlığı açısından incelendi. Epidermoid karsinom ve keratokist olgularının % 90'ında, foliküler kist olgulannin % 60'mda ve radiküler kist olgularının ise % 50'sinde EGFR varlığı gözlendi. Bu sonuçlara dayanarak EGFR'nün epitel malignitesi-ni belirleyici özelliğe sahip olabileceği görüşüne vardık.
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  • Turkish

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