Buradasınız

Anasayfa » Content

DİYALİZ AMİLOİDOZU VE BİLEK KANALI SENDROMU

DIALYSIS AMILOIDOSIS AND CARPAL TUNNEL SYNDROME

Journal Name:

  • Türk Nefroloji, Diyaliz ve Transplantasyon Dergisi

Publication Year:

  • 2001

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
ESRD patients' expected survival increased with the amelioration of the quality of care in both long term HD and CAPD. Beta -2 microglobulin type dialysis amiloidosis and its clinical manifestations like osteo articular, norologic symptoms and signs and CTS are frequently seen in these patients especially those with longer dialysis durations. In these study CTS which is the most important finding of DA, frequency and the associated parameters are evaluated. The presence of CTS was evaluated by EMG in 48 patients (29 male, 19 female) undergoing chronic dialysis (30 HD, 18 CAPD) . The CTS was ascertained in 18patients (37,5 %). The associations between CTS and patients age , sex , dialysis durations, arthritis, arthralgias, symptoms and signs of CTS, levels of serum ferritine CRP and intact PTH were evaluated in all patients. As a cosequence about all of these parameters only serum ferritine levels had a strong statistically meaningfull association with CTS. (p=0,02)
Bookmark/Search this post with
Abstract (Original Language): 
Hemodiyaliz (HD) ve Sürekli Ayaktan Periton Diyalizi (SAPD) tedavilerindeki iyileşmeler sonucunda diyaliz sürvileri uzayan Son Dönem Böbrek Yetersizliği (SDBY) hastalarında Diyaliz Amiloidozu (DA) ve neden olduğu başta Bilek Kanalı Sendromu (BKS) olmak üzere çeşitli nörolojik ve osteoartiküleryakınma ve bulgular sıklıkla karşımıza gelmektedir. Bu çalışmada DA 'unun en sık ve en önemli bulgusu olan BKS unun sıklığının ve DA oluşumuna etki edebilecek çeşitli parametrelerin BKS'na etkisinin incelenmesi amaçlanmıştır. Bu amaçla toplam 48 kronik diyaliz hastası (30 HD ve 18 SAPD) (19 kadın ve 29 erkek) çalışmaya alındı. Çalışmaya alınan hastaların tamamına EMG yapılarak toplam 18hastada (% 37,5) BKSsaptandı. Bu 48 hastanın tamamında BKS ile yaş, cinsiyet, BKS muayene bulgusu, artralji, artrit serum PTH, CRP ve ferritin seviyeleri arasındaki ilişki araştırıldı. Sonuç olarak BKS ile araştırılan parametreler arasından sadece ferritin ile arasında güçlü bir istatistiksel bağlantı olduğu ortaya çıktı, (p=0,02)
FULL TEXT (PDF): 
PDF icon pdf_tndt_323.pdf
  • 1
45-48
  • Turkish

REFERENCES

References: 

1. Kleinman K. S., Coubıırn J. W. Amyloid syndromes associated with hemodialysis. (Editorial Review) Kidney Int. 1989; 35 : 567-575.
2. Zingraff J. . Drueke T. Can the Nephrologist prevent dialysis related amyloidosis ? Am. J. Nephrol. 1991 ; 8: (I): 1-11.
3. Koch Karl M: Dialysis related amyloidosis. Kidney Int. 1992:41: 1416-1429.
4. Spertini F. , Wauters J.P. . Poulenas I. Carpal Tunnel Syndrome a frequent, invalidating long term complication of hemodialysis. Clin. Nephrol. 1984 ; 21:98-101.
5. Schwartz A., Keller F.. Seyfert S. .et al. Carpal Tunnel Syndrome : a major complication in long term
hemodialysis patients. Clin. Nephrol. 1984 : 22 : 133¬137.
6. Warren D. J. , Otieno L.S. Carpal Tunnel Syndrome in patients on intermittent hemodialysis. Post. Grad. Med.
J. 1975:51:450.
7. Stein G. , Schneider A. , Thoss K. .et al. Beta - 2 -microglobulin- derived amyloidosis:onset, distrubution, and clinical features in 13 hemodialysis
patients . Nephron 1992 ; 60 : 274-280.
8. Allain G. , Calemard E. , Charra B. Dilysis related
amyloidosis. Kidney Int. 1988 : Vol 33 supp. 24 : 32¬34.
9. Sungur C , Sivrin A., A. Sungur ve ark.Early Detection of CTS by electroneurophysiologic studies in chronic hemodialysis patients. Nephron 1994:67 : 114Editorial.
Diagnosis of CTS . Lancet 1985 ; i. 854-855.
10. M. Jadoul , C. Garbar . H. Noel . J. Sennesael , R.
Vanholder , P. Bernaert, G. Rorive . G. Hanique . C. V. Y. D. Strihou: Histological prevalence of â2-microglobulin amyloidosis in hemodialysis: a prospective post-mortem study. Kidney Int. 1997 ; 51 : 1928-1932
11. Strihou . C. V. Y. D, Jadoul M. Malghem J., Maldegue B., Jamart J and the working party on dialysis amyloidosis : Effects of dialysis membrane and patient's age on signs of dialysis related amyloidosis.
Kidney Int. 1991 ; 39 :1012-1019.
12. Zaoui P. M. , Stone W. J. , Hakim R. M. Effects of
dialysis membranes on beta2-microglobulin
production. Kidney Int. 1990 ; 38 : 962-968.
13. Schwalbe S. , Holzhauer M . , Schaeffer J., M.
Galanski, Koch K. M , Floege J. â2-microglobulin associated amyloidosis :a vanishing complication of long term hemodialysis? Kidney Int. 1997 ; 52 : 1077¬1083
14. Benz , J. W. Siegfried , B. P. Teehan : CTS in dialysis patients xomparison between CAPD and hemodialysis populations . Am. J. of Kidney Dis. 1988 ;Vol 11:6: 473-476.
15. Tielemans C. , Dratwa M., Bergmann P. , Goldman M,
B. Flamion, Collart F, Wens R. CAPD vs
hemodialysis: a lesser risk of amyloidosis? Nephrol.
Dial. Transplant. 1988 ; 3 : 291-294.
16. Sethi D., Murphy C. M. B. , Brown E. A.,. Müller B.
R.. Gower P. E. Clearance of beta-2- microglobulin
using CAPD.Nephron 1989;52:352-355.
17. Strihou C. , Nicola L. D., Nicola T. , Simone W. D. . . Memoli B. Inflamatory effects of peritoneal dialysis : evidence of systemic monocyte activation. Kidney Int.
1996;49:506-511.
18. Jadoul M, Noel H. , . Strihou C. V. Y. D. â2 -
microglobulin amyloidosis in a patient treated
exclusively by CAPD. Am. J. Kidney Dis. 1990 ; Vol 15: I : 86-88.
19. Stein G. , Schneider A. . Thoss K et al. Beta 2-
microglobulin serum concentration and associated amyloidosis in dialysis patients. Nephrol. Dial. Transplant. 1991 ;6suppş3: 57-61.
20. Nakazawa R., Hamaguchi K., Hosaka E., Shishido H., Yokoyama T. Cutaneous oxalate deposition in ahemodialysis patient. Am. J. Kidney Dis. 1995 ; 25
(3): 492-497.
21. Ford P. M. Arthropathies associated with renal disease including dialysis related amyloid. Curr. Opin.
Rheumatol. 1992;4(l):63-67.
48

Thank you for copying data from http://www.arastirmax.com