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İntihar amaçlı karbamazepin entoksikasyonu: Olgu sunumu

Carbamazepine intoxicatio n as a suicidal attempt: a case report

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DOI: 
doi:10.2399/tahd.08.104
Abstract (2. Language): 
Carbamazepine intoxication is a frequently encountered and life threatening condition in emergency services. The medical interventions towards carbamazepine intoxications were reviewed related to a 24-year-old woman who ingested a high dose of carbamazepine for suicidal attempt. Neurologic and cardiac side effects are emergent problems due to carbamazepine intoxication and should be taken under control as soon as possible. Other therapeutic interventions are giving repeated doses of activated charcoal and early hemoperfusion.
Abstract (Original Language): 
Karbamazepin zehirlenmeleri acil servislerde sık karşılaşılan ve yaşamı tehdit eden bir sorundur. intihar amacıyla yüksek doz karbamazepin alan 24 yaşında bir kadın olgu nedeniyle bu tür zehirlenmelere medikal yaklaşım gözden geçirilmiştir. Karbamazepin zehirlenmelerinde nörolojik ve kardiyak yan etkiler en acil sorunlardır ve en kısa sürede kontrol altına alınmalıdır. Diğer tedavi yaklaşımları tekrarlayan dozlarda aktif kömür verilmesi ve erken dönemde hemoperfüzyondur.
104-106

REFERENCES

References: 

1. Spiller HA, Carlisle RD. Status epilepticus after massive carbamazepine overdose. J Toxicol Clin Toxicol 2002; 40: 81-90.
2. Graudins A, Peden G, Dowsett RP. Massive overdose with controlled-re-lease carbamazepine resulting in delayed peak serum concentrations and life-threatening toxicity. Emerg Med 2002; 14: 89-94.
3. American Academy of Clinical Toxicology; European Association of Poi¬sons Centres and Clinical Toxicologists. Position statement and practice guidelines on the use of multi-dose activated charcoal in the treatment of acute poisoning. J Toxicol Clin Toxicol1999; 37: 731-51.
4. Durelli L, Massazza U, Cavallo R. Carbamazepine toxicity and poisoning: incidence, clinical features and management. Med Toxicol Adverse Drug Exp 1989; 4: 95-107.
5. Low CL, Haqqie SS, Desai R, Bailie GR. Treatment of acute carbamaze-pine poisoning by hemoperfusion. Am J Emerg Med1996; 14: 540-1.
6. Soderstrom J, Murray L, Little M, Daly FM. Toxicology case of the month: carbamazepine overdose. Emerg Med J2006; 23; 869-71.
7. Serin S, Erbay H, Metinöz H, Atalay H. Barbeksaklon ve karbamazepin zehirlenmesinde yoğun bakım (olgu sunumu). Toksikoloji Dergisi 2005; 3:
13-7.
8. Tapolyai M, Campbell M, Dailey K, Udvary-Nagy S. Hemodialysis is as effective as hemoperfusion for drug removal in carbamazepine poisoning.
Nephron 2002; 90: 213

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