You are here

Home » Content

NİFEDİPİN TEDAVİSİNE BAĞLI ORTAYA ÇIKAN DİŞ ETİ BÜYÜMESİ (OLGU SUNUMU)

GINGIVAL HYPERPLASIA CAUSED BY NIFEDIPINE (A CASE REPORT)

Journal Name:

  • Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi

Publication Year:

  • 2006

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
Nifedipine is an increasingly used medication for treatment of angina pectoris and arterial hypertension. Nffedipine-induced oral compilations may develop; also gingival hyperplasia is one of the most important among these. In this study, one case of gingival hyperplasia associated with long-term administration of nifedipine, a drug that dilates coronary arteries, is reported. Extensive dental plaque control in addition to surgical removal of the overgrowed gingival tissues resulted in satisfactory progress without the need to discontinue drug administration. In this case report, clinical features, etiology, differential diagnosis and treatment of nffedipine-induced gingival hyperplasia have been discussed in light of literatures.
Bookmark/Search this post with
Abstract (Original Language): 
Nffedipnn, arteriyal hipertansiyon ve angnna pektoris tedavisinde sıklıkla kul/anılan bir ajandır. Nifedipine bağlı oral kompiıkasyon/ar gelişebilir ki, bunaardan dişeti büyümesi en önemlllerindendir. Bu çalışma, koronor arterlerin dllatasyonunda kullanılan önemi i brr laç olan nifedipinin uzun dönem kullanımına bağlı geiişen dişeti büyümesi şikayetiyle kiniğimize başvuran brr bayan hastanın vaka raporudur. Vakada büyüyen dişeti dokularının cerrahi oaarak uzaklaştırılması ve dikkatli plak kontroüü lie ilacın kullanımının kesilmesine gerek duyulmadan yeterli iyileşme sağlanmıştır. Bu çalışmada nifedipine bağlı geiişen dişeti büyümesinin kiinik özelikkleri, etiolojisi, ayrrcı tansı ve tedavisi, konuyla llişkili kaynaklar ışığında tartışılmıştır.
FULL TEXT (PDF): 
PDF icon arastirmax-nifedipin-tedavisine-bagli-ortaya-cikan-dis-eti-buyumesi-olgu-sunumu.pdf
  • 1
59-62
  • Turkish

REFERENCES

References: 

1. Brunet L, Mrranda J, Farre M, Berini L, Mendieta C. Gingival enlargement induced by drugs. Drug Saf. 1996;15(3):219-31.
2. Tack DA, Rogers RS. Oral drug reactions. Dermato/ogic Therapy2002;15:236-250.
3. Desai P, Sliver JG: Drug-induced gingival enlargements. J Can Dent Assoc.1998; 64(4)263-268.
4. Ciantar M. Nifedipine-induced gingival overgrowth: remission following non-surgical therapy. Dent Update. 1996;23(9)374-377.
5. Katz J, Rotstein I, Ben Yehuda A, Barak S. Nffedipine-induced gingival hyperplasia. Ann Dent.1992;51(1):5-7.
6. Bokor-Bratic M, Vuccovic N, Se/akovic S. Gingival hyperplasia during treatment with nifedipine: Med Pregl. 1998;51(9-10): 445¬448.
7. Angelopolous AP, Goaz PW. Incidence of diphenylhydantonn gingival hyperplasia. J Oral Surg 1972; 34:898-906.
8. Barak S, Engelberg IS, Hiiss J. Gingival hyperplasia caused by nifedipine (Histopathologic findings). J Periodontal 1987; 58(9): 639-642.
9. Thomason JM, Seymour RA, Rice N. The prevalence and severity of cyc/osporin and nffedipine-induced gingival overgrowth. J Clin Periodontal 1993;20(1):37-40.
10. Thomason JM, Seymour RA, Elfis JS, Keiy PJ, Parry G, Dark J, Idee JR. Iatrogenic gingival overgrowth in cardiac transplantation. J Periodontal 1995; 66: 742-746.11. Hasse// TM, Hefti AF. Drug-induced overgrowth: Old probeem, new problem. Crtt Rev Oral Biol Med 1991; 2:103-137.
12. Nishikawa S.,Tada H., Hamasaki A.,et al. Nifedipfne-induced gingival hyperplasia: A cinnical and nn vitro study. J Periodontal 1991; 62:30-35.
13. Hasse// T, Sobhani S. Effects of diphydropyrfdines on connective tissue cells in vitro. J Dent Res 1987; 66 (Spec. Issue): 282(Abstr. 1401).
14. Hefjl L, Sundin Y. Nifedipfne-induced gingival overgrowth in dogs. J Periodontal 1988; 60: 104-112.
15. Bui/on P, Machuca G, Armas JR, Rojas JL, Jimenez G. The gingival inflammatory inf ltrate in cardiac patients treated with calcium antagonists. J Cinn Periodontal 2001; 29: 897¬90.

Thank you for copying data from http://www.arastirmax.com