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2 CM’DEN BÜYÜK ÜRİK ASİT TAŞLARINDA ORAL KEMOLİZ

Journal Name:

  • Cerrahpaşa Tıp Dergisi

Publication Year:

  • 2005

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
By medical chemolysis, uric acid calculus can be dissolved and their recurrences can be avoided. Between 2000 and 2004, 12 patients applied to our clinics with uric acid calculus larger than 2 cm. We treated these patients with adequate hydration and potassium citrate (1 mEq/kg/day). For those who can not tolerate potassium citrate, sodium bicarbonate (650 mgr 3-4 times a day) was started. Each patient was given a pH paper to record urinary pH, and drug dozes were titrated until urinary pH 7.0 was reached. Allopurinol (300mgr/day) was given to the ones with hyperurisemia. Patients were followed-up with urinary sediment, urinary culture, and ultrasonography and/or computerized tomography. Results.- Mean age of the patients were found to be 51 (34-70). Eight patients had left, 4 had right kidney stone. One patient had solitary kidney. Mean stone size were 29 mm (20-40). All of the stones were dissolved in 3.7 (2-6) months. None of the patients had urinary infection through out of the treatment.
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Abstract (Original Language): 
Medikal kemoliz ile ürik asit taşları eritile-bilir tekrarlaması engellenebilir. Bu bilgiler ışı-ğında kliniğimize 2000 ile 2004 tarihleri ara-sında 2 cm’den büyük ürik taşı ile başvuran 12 hastaya yeterli hidrasyon ve potasyum sitrat (1 mEq/kg/gün) tedavisi başladık. Potasyum sitra- CERRAHPAŞA TIP DERGİSİ Cilt (Sayı) 36 (2) 68 tı tolere edemeyen hastalarda sodyum (650 mgr günde 3-4 kez) bikarbonat tedavisine ge-çildi ve bu hastalar prospektif olarak takip edil-di. İdrar pH’ları kontrol edilerek 7,0 olacak şe-kilde doz ayarlaması yapıldı. Hiperürisemisi saptanan 3 hastaya ise Allopurinol (300 mgr/ gün) başlanıldı. Ortalama taş yükü 29 mm (20-40) olan has-taların hepsinin aşları ortalama 3.7 (2-6) ayda eritildi. Anüri ile başvuran soliter böbrekli 1 hasta dışında hiçbir hastaya kateter takıldı. Sonuç olarak oral kemoliz 2 cm’den büyük ürik asit taşlarında da güvenle kullanılabilecek bir yöntemdir.
FULL TEXT (PDF): 
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  • 2
65-68
  • Turkish

REFERENCES

References: 

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