“THE ADHERENCE OF CANDIDA ALBICANS ON SURFACE OF DIFFERENT DENTURE BASE MATERIALS (AN IN-VITRO STUDY)”

(1) Devarhubli AR, Subbarao VK, Patil NP. Surface adherence of Candida albicans to different polymethyl
methacrylate resin denture base materials. World Journal of Dentistry 2011;2(3):237-42.
(2) Davenport JC. The oral distribution of Candida in denture stomatitis. Brit Dent J 1970;129:151.
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used for this study were self cure acrylic resin, heat cure
acrylic resin and chrome cobalt base metal alloy. Acrylics
and metals have been used in the fabrication of denture
bases; however, acrylics have been more widely used.
Acrylics though economical and easy to manipulate,
show some features such as water sorption and
permissive surface in contrast to metallic denture bases.9
These features may alter the degree of adherence of
Candida albicans to acrylics, which may be contrasting to
the metals. Among the metals, gold has been shown to
have better surface topography than acrylics.10 However,
the use of gold is impracticable. Therefore, chrome
cobalt, a commonly used metallic denture base material,
is been used in this study.
The methodology chosen here was based on a
study by John F. Miner(1973) with following
modifications. An incubation period of 48 hours was
considered for all the specimen groups. Therefore, the
adherence of the cells was observed only for the tissue
surface of the specimens, keeping in mind of the fact that
Candida albicans is mainly seen thriving in this surface.11
The polished surface of a denture on the other hand,
presents a smooth and glossy texture, which is not much
capable of harboring fungi and bacteria as compared to
the rough surface.12 Moreover, the unpolished fitting
surface is more capable of absorbing infected oral fluids
than the polished surface, thus creating a suitable
environment for the microorganisms to grow.13
CONCLUSION :
The following conclusions were drawn from our present
study :
1. Chrome cobalt alloy denture base material showed less
adherence of candidial cells compared to heat cure and self
cure acrylic resin denture base materials.
2. Among the acrylics, heat cure acrylic resin showed
comparatively less adherence of candidial cells than self cure
acrylic resin.
Above findings suggest that the metallic denture bases are
far better than acrylic denture bases in terms of incidence of
denture stomatitis due to candidial infection. Further, they are
seemed to be more biocompatible with the oral tissues with
minimal tissue reactions if any.14 However, usage of these
base metal alloys as denture bases may not be practicable in
regard to their cost, difficulty in relining the necessary set up
for their fabrication. Thus, acrylic resins still remain the
materials of choice answering the requisites of economy and
ease of fabrication. However, patient’s oral hygiene should
be given prime importance irrespective of the denture base
materials used.
Indian Journal of Basic & Applied Medical Research; March 2013: Issue-6, Vol.-2, P. 576-581
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(4) Olsen Ingar. Denture stomatitis; Occurrence and distribution of fungi. Acta Odont Scand 1974;32:329-33.
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(11) Kalla R, Rao H, Sunilkumar MV. Surface adherence of Candida Albicans to different
polymethylemethacrylate denture base resins. International Journal of Prosthetic Dentistry 2011;2(1):2-7.
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