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DEVELOPMENT OF UV SPECTROPHOTOMETER METHOD OF CARVEDILOL IN BULK AND PHARMACEUTICAL TABLET DOSAGE FORMULATION

Journal Name:

  • The International Journal of Pharmaceutical Research and Bio-Science

Publication Year:

  • 2013

Key Words:

Author Name
Abstract (2. Language): 
The simple, precise and economic UV methods have been developed for estimation of Carvedilol in single component. Carvedilol has the absorbance maxima in zero order spectra in 230 nm (method A). Method B applied was first order derivative for the analysis of Carvedilol at 238.5 nm .Method C applied was area under curve in the wavelength range of 234-228 nm. Drug followed Beer-Lamberts law in the concentration range of 503.5 u.g/ml for zero order, 10-60 u.g for area under curve methods and first order derivative spectrum. The percentage recovery of Carvedilol ranged from 98.05 to 101.075 in pharmaceutical dosage from result of analysis was validated statistically and by recovered study.
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  • 1
342-348
  • English

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Available Online At www.ijprbs.com
Research Article
Poonam Bhange, IJPRBS,
2013; Volume 2(1): 342-348
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ISSN: 2277-8713 IJPRBS
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