You are here

TÜKÜRÜKTEKİ AMİLAZ AKTİVİTESÎNE SİGARANIN ETKİLERİ

THE EFFECT OF CIGARETTE SMOKING ON SALIVARY AMYLASE ACTIVITY

Journal Name:

Publication Year:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
In this study, the effects of cigarette smoking on salivary amylase activity has been investigated by using Wohlgemuths's methods on 40 smoking and nonsmoking persons and it has been found that there is a significant increase in amylase activity in cigarette smoking group. However there has not been found any significant differences İn amylase activity related to sex. It has been thought that the increase of amylase activity is related with neurovascular reflex and stimulation oj reseptors which are on oral, lingual andfaryngeal mucosa by irritation of smoking.
Abstract (Original Language): 
Bu çalışmada sigara içen ve içmeyen toplam 40 sağlıklı kişide sigaranın tükürükteki amilaz aktivitesine etkileri Wohlgemuth yöntemi kullanılarak araştırılmış ve sigara içenlerde tükürükteki amilaz aktivitesinin anlamlı bir şekilde arttığı (P<0.001) istatistiksel olarak tesbit edilmiştir. Ancak cinsiyete bağlı olarak amilaz aktivitesinde anlamlı bir fark bulunmamıştır. Tükürükteki amilaz aktivitesinin artışı sigaranın nöro-vasküler refleks ve irritasyonla ağız, dil, farinks mukozasındaki reseptörleri uyarmasına bağlanmıştır.
138
142

REFERENCES

References: 

1.
Akçastı
, A.: Farmakoloji ve Tedavi, Kutulmuş Matbaası, İstanbul, 1973.
2. Bennet, R., Reade, P.C.: Salivary immunoglobulin A levels in normal subjects, tabocco smokers and patients with minor aphthous ulceration, Oral Surgery, 1982; 53: 461-465.
3. Cailegari, G, et al: Cigarette smoking and salivary amylase activity, Gut. 1984; 25 (8): 909.
4.
Derman
, H., Emİroğlu, F.: Özet Fizyoloji, Baha Matbaası, İstanbul, 1968.
5. Geachin, R.L., Hay, P.A., Prell, P.A.: Comparison of salivary amylase levels in the human male and female, Nature, 1965; 208:1211-1212.
6. Gillard, B.K., Simbala, J.A. and Goodglick, L.: Reference intervals for isoenzymes in serum and plasma of infants and children, 1983; 29:1119-1123.
7. Gilman, A.G., Goodman, L.S., Gilman, A.: Goodman and Gilman's The Pharmacological Basis of Therapeutics, 6. Baskı, Macmillan Publishing Co. Inc., Newyork, 1980.
8.
Irmak
, S., Gökhan, N., Emiroğlu, F.: Fizyoloji, Sermet Matbaası, İstanbul, 1972.
9. İkeno, T-, Nasa, J., Kuzuya, H.: Quantitative changes in amylase activity in the salivary glands, pancreas, saliva and serum after administration of isoproterenol, pilocarpin and acetylcholin, LDent. Res. 1983; 62: 56-57.
10.
İyigün
, T.: Sitostatik tedavisi gören hastalarda tükürükteki değişiklikler, Doktora tezi, İstanbul, 1986.
11. Jacobsen, N.: Salivary amylase, Caries Res., 1970; 4: 200-205.
12. Jenkins, G.N.: The Physiology and Biochemistry of the Mouth, 4. Baskı, Blackwell Scientific Publications, Oxford, 1978.
13. Larsen, L.R., Schaller, D.E.: Wound amylase levels as an early indicator of orocutaneous fistulae, Laryngoscope, 94; 1302-1306, 1984.
14. Lavelle, C.L.B.: Applied Physiology of the Mouth, Wright, Bristol, London, 1975.
15. Main,'B.E., Caiman, K.C., Fergusson, M.M., Kaye, S.B., Mac Farlane, T.W., Mairs, R.j., Samaranayake, L.P., Wiliox, J., Welsh, J.: The effect of cytotoxic therapy on saliva and oral flora, Oral Surgery, 1984; 58: 545-548.
16.
Özalp
, A.E.: Diş Hekimliği Kliniğinde Farmakoloji, Taş Matbaası, İstanbul, 1985.
17. Rossiler, M.A., Barrowman, J.A., Dand, A. and Wharton, B.A.: Amylase content of mixed saliva in childcrcn, Acta. Pediatr. Scand., 1974; 63: 389-392.
18. Yenson,
M.
: Klinik Bİokimya Laboratuvar Çalışmaları, 5. Baskı, Sanal Matbaacılık, İstanbul, 1982.

Thank you for copying data from http://www.arastirmax.com