A HISTOPATHOLOGICAL
EVALUATION
AND
COMPARISON OF THE BIOCOMPA T ABILITY OF THREE DIFFERENT HEMOSTA TIC AGENTS IN THE EARLY STAGE HEALING OF EXPERIMENTAL BONE DEFECTS
Journal Name:
- İstanbul Üniversitesi Diş Hekimliği Fakültesi Dergisi
Keywords (Original Language):
| Author Name | University of Author | Faculty of Author |
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Abstract (2. Language):
In this study, the effects of three different hemostatic agents in the early stage of healing of experimental bone defects and their biocompatability were compared. Four bone defects were prepared simetrically in Wistar albino rat tibias, aged 4-6 months. Bonewax, spongostan, surgical, were placed in three defects respectively, while the fourth one was allowed to fill with blood to serve as the control. After histopathological evaluation, it was found that surgicel and spongostan were more biocompatible when compared with bonewax. However, it was concluded that all of the materials had negative effects in the early stage oj healing.
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Abstract (Original Language):
Bu çalışmada üç farklı hemostatik maddenin biokompati-bilitesi ve kemik iyileşmesinin erken dönemindeki etkileri incelenmiştir. 4-6 aylık Wistar albino sıçanlarının tibiaları-na simetrik olarak dört defekt oluşturulmuş ve içlerine bo-newax, spongostan ve surgicel yerleştirilmiş, bir defekt kontrol için boş bırakılmıştır. Yapılan histopatolojik tetkikler sonucunda spongostan ve surgicel'in bonewax'a oranla daha fazla biokompatıbl olduğu görülmüştür, ancak her üç materyalin de iyileşmenin erken döneminde olumsuz etkileri olduğu saptanmıştır.
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