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Kronik Böbrek Yetmezliğinin Nadir Bir Nedeni: Kronik Lityum Kullanımı

Chronic Lithium Use As a Rare Cause of Chronic Renal Failure

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DOI: 
DOI 10.5262/tndt.2012.1003.23
Abstract (2. Language): 
Lithium is the treatment of choice in bipolar disorders. Long-term use has important side effects such as nephrotoxicity. A 37-year-old female patient on lithium with proteinuria and renal failure was diagnosed as having chronic tubulointerstistial nephritis and secondary focal segmental glomerulosclerosis at renal biopsy. These fi ndings were linked to lithium use. We present this case as it is a rare event.
Abstract (Original Language): 
Lityum, bipolar bozuklukların tedavisinde kullanılan en etkin ilaçtır. Uzun süreli kullanımda önemli yan etkileri vardır ve nefrotoksisite bunlardan birisidir. Otuz yedi yaşındaki bayan hasta, proteinüri ve böbrek yetmezliği nedeniyle tetkik edildi ve böbrek biyopsisinde kronik tübülointerstisyel nefrit ve sekonder fokal segmental glomerülokleroz saptandı. Bulgular lityum kullanımına bağlandı. Biz bu olguyu literatürde nadir olması nedeniyle sunuyoruz.
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