You are here

DOĞU KARADENİZ BÖLGESİNDE ÇOCUKLUK ÇAĞINDA AKUT GLOMERULONEFRİT

ACUTE GLOMERULONEPHRITIS IN CHILDHOOD IN THE EASTERN BLACK SEA REGION

Journal Name:

Publication Year:

Keywords (Original Language):

Abstract (2. Language): 
Tlıe present study was carried out in 93 children with acute glomerulonephritis admitted to the pediatrics department of Karadeniz Technical University Faculty of Medicine, Trabzon. Of these patients 35 were females and 58 were males aged between 2 and 16 years. Edema (92.4%), macroscopic hematuria (70.9%), oliguria (29.0%) and vomiting (32.3%) were the most common findings at admission. Pyodermia was present in 46 cases in the past history, and upper respiratory tract infection in 28 cases. Hepatitis B in 3 cases, mumps in one case and otitis media in another case were the other associated diseases. Daily protein excretion was under 2gr/day in all cases. BUN values were above 20mg/dl in the 39 cases. ASO and CRP were positive in 19 and 21 cases , respectively. Pulmonary congestion was recorded in 43 cases with the association of pleural effusion in 6. 89 cases had low C3 levels and these values returned to normal in 8.9±5.5 weeks. Tliere were radiological abnormalities on abdominal ultrasonog-raphy in 25 of the cases and intravenous pyelography abnormalities were seen in 13 patients. One patient died due to severe intractable cardiac failure and pulmonary edema in the hours of admission. The microscopic hematuria continued more than one year in patient of 10 years old. No complication was determined in the other patients during the follow-up period.
Abstract (Original Language): 
Bu çalışma 1989 ile 1993yıllan arasında Karadeniz Teknik Üniversitesi Tıp Fakültesi Pediatri Ana Bi¬lim Dalında atut glomendonefrit tanısı ile tatip edilen 58i erkek,35'i kız olmak üzere toplam 93 hastanın dos¬yalarının incelenmesiyle yapıldı. Hastalarda ençok gö¬rülen bulgular ödem (%92.4), hematüri (%70.9) oligüri (%29.0) ve kusma (%32.3) idi.Vakalann %46.9'unda pyodemü,%30,l'inde ÜSYE saptanırken,%3.2'sinde hepatit, %1.l'inde kabakulak ve %1.l'inde otit hikayesi mevcuttıı,%12.9'unda ise etyolojikneden saptanamadı. Semptomlarla kliniğe başvunı arasındaki süre 7.1+5.0 gündü. Vakalann tümünde günlük protein atılımı 2gr/dl'nin altındaydı. Vakaların %41.9'unda üre de¬ğeri 20 mg'ın üzerinde saptanırken,%20.4'ünde ASO pozitifliği, %22.6'sında CRPpozitifliğisaptandı.Vakala-nn %46.2'sinde akciğergraflsinde staz ile uyumlu görii-nüm mevcııtken,%6.5'unda pleural efüzyon belirlendi. Vakaların %95.7'sinde C3 düşüklüğü belirlendi ve 8.9+5.5 haftada nomıal düzeyler eriştiği saptandı.93 va¬kanın 25'inde (%26.9) batın ultrasonografisinde, 13'ün-de (%13.9) ise intravenöz pyelografi'de çeşitli radyolo¬jik patolojiler saptandı.Klinik takip sırasında bir vaka yatışının 4'üncü saatinde kalp yetmezliği ve akciğer ödemi ile exitus oldu.Diğerbir vakada mikroskopik hematü-ri 3 yıl devam etti. Kalan vakaların klinik takiplerinde komplikasyon saptanmadı.
FULL TEXT (PDF): 
49-52

REFERENCES

References: 

1-
Rodriguez-Bernardo,Garci
a IR:isolated glomerular diseases inıClinical Nephrology.Edited by Holiday MA, Barrat TM, Verniere RT. Chapter:26,Second edition,Baltimore, Williams-Wilkins, 1987;pp 407-420.
2- Jordan SC, Lemire JM, FRCP:Acute Glomerulonephritis.The
pediatric clinics of North America 29 (4):857-873,1982.
3-
Yasavu
l Ü,Turgan Ç,Çağlar Ş:Glomeruler hastalıklar. Klinik Nefroloji. 2.baski,bölüm 10, 1986;s.l55-172.
4-
Beşba
ş N, Saatçi Ü:Akut poststreptokoksik glomerulonefrit ve izlemi.Katkı Pediatri dergisi 7 (4):285-287,1986.
5- Jordan SC, Buckingham B,Sakai R,et al:Studies of immune complex glomerulonephritis, mediated by human thyroglobulin. N Engl J Med 304: 1212-215,1981.
6- Sheipac LN, Boickok Luvenets KA, Fesenko W:The clinical course of acute glomerulonephritis in transbaikalia. Voen Med zh 80 (11):38-39,1992.
7- Stetson CA,Rammelkamp CH,Krause RM, Kohen JR, and perry WD: EPIDEMIC acute nephritis:studies on etiology natural history and prevention. Medicine 34:431,1975.
8- Dillon HC, Streptokokal infection of the skin and their complications; impetigo and nephritis. IN: streptococci and Streptococcal disease.Edited by Wannamaker LW and Matsen JM, New York.Academic press,1972,571.
9- Rimediotti NJ.Bianchetti MG, Penzien JM, Matter L, Luthi C, Zimmerman A,Oettiker OH. Glomerulonephritis with Transient C3 hypocomplementemia and endotheliomesangial glomerulonephritis in childhood. A long-term experience
Schewerz Med Wochenschr 122 (47): 1803-1809,1992.
10- Rodriguez Iturbe B, Castillo L, Valbvena R, Et al; Acute poststreptococal glomerulonephritis a rewiev of recent developments. Paediatrician. 8: 307,1979.
11- Schwartz WB, Kassier JP;Clinical aspect of acute poststreptococcal glomerulonephritis.In Disease of the
kidneys. Edited by Strauss MB, Welt LG,ed 2. Boston, Little-Brown-Co, 1971:pp,419.
12- Monhart V, Jaros M, Incidence of arterial hypertension during and after acute glomerulonephritis.Vnitr Lek 37 (1);48-521,1991.
13- Schreiner GE, Rahowski TA, Argy WP et all. Natural history of oliguric glomerulonephritis. In Glomerulonephritis Morphology, Natural history and treatment. Edited by Kincaid-Smith P, Mathew TH, Becher LL, Part II, New York, John Wiley and Sons 1977; pp: 711.
14- Friedment R, Benderly A, Golan D, Levy J, Etziari A. Blood level of C3 complement as an aid in the management of acute
phase Glomerulonephritis. Isr J Med Sci 1985;21:118-212.
15- Levy M, Sich M, Piroztzky E, Habib R. Complement activation in acute Glomerulonephritis in children. Snt J Pediatr Nephrol 1985;6:17-24.
16- Powell HR, Me Credie PA, Rotenberg E. Response to furosemide in acute renal failure: Dissociation of renin and diuretic responses. Clin Nephrol 1980; 14:55.
17- Çağlar MK, Dilmen U, Senses DA, Kınık E, Barlak A. Sodium Nitroprusside for hypertensive emergencies in children. The Turkish Journal of Pediatries 1986;28:97-103.

Thank you for copying data from http://www.arastirmax.com