You are here

Preemptif ve non-Preemptif Renal Transplant Alıcılarının Sonuçlarının Karşılaştırılması

The Comparison of Results of Preemptive and non-Preemptive Transplant Recipients

Journal Name:

Publication Year:

Abstract (2. Language): 
Transplantation is defined as preemptive if it takes place before the initiation of chronic dialysis treatment. 8 (4.4%) preemptive kidney transplantations were performed in our center at that time. Preemptive and non-Preemptive renal transplant recipients included into the study. In both groups, graft functions and the frequency of medical and surgical complications were compared in one-year period. There was four acute rejection episodes in Preemptive patients and one delayed graft function in non-Preemptive patients. In preemptive patients the mean creatinine levels at 1 and 12 months were 1.3 ± 0.5 and 1.5 ± 0.6 mg/dl, and in non-preemptive patients 1.2 ± 0.2 and 1.3 ± 0.3 mg/dl. The ratios of medical and surgical complications were similar. Preemptive kidney transplantation is suggested in the selected endstage renal disease patients.
Abstract (Original Language): 
Transplantasyon kronik diyaliz tedavisi başlanmadan önce yapılırsa preemptif olarak tanımlanır. Merkezimizde şu ana kadar 8 (%4.4) preemptif böbrek transplantasyonu yapıldı. Preemptif ve non-Preemptif renal transplant alıcıları çalışmaya dahil edildi. Her iki grupta 1 yıllık dönemde graft fonksiyonu, medikal ve cerrahi komplikasyonların sıklığı karşılaştırıldı. Preemptif hastalarda 4 akut rejeksiyon atağı, non-Preemptif hastalarda 1 gecikmiş graft fonksiyonu vardı. Preemptif hastalarda 1. ve 12. ayda ortalama kreatinin seviyeleri 1.3 ± 0.5 ve 1.5 ± 0.6 mg/dl, non-Preemptif hastalarda 1.2 ± 0.2 ve 1.3 ± 0.3 mg/dl idi. Medikal ve cerrahi komplikasyon oranları benzerdi. Preemptif böbrek transplantasyonu, son dönem böbrek hastalığı olan uygun hastalarda düşünülmelidir
83-86

REFERENCES

References: 

1. Lysaght MJ. Maintenance dialysis population dynamics:
current trends and long-term implications. J Am Soc Nephrol
2002;13(Suppl.1):S37-40.
2. http://www.who.int/entity/transplantation/organ/en/WHO
website (February 2006)
3. Wolfe RA, Ashby VB, Milford EL et al. Comparison of
mortality in all patients on dialysis, patients on dialysis
awaiting transplantation, and recipients of a first cadaveric
transplant. N Engl J Med 1999;341:1725-30.
4. Kasiske BL, Snyder JJ, Matas AJ, Ellison MD, Gill JS, Kausz
AT. Preemptive kidney transplantation: the advantage and the
advantaged. J Am Soc Nephrol 2002;13:1358-64.
5. Glotz D, Chalem Y, Ryckelynck JP, Verger C, Tuppin P. The
influence of modality of treatment of end-stage-renal disease
on access to and results of kidney transplantation (Abstract). J
Am Soc Nephrol 2003;14(Suppl):187A.
6. Girndt M, Sester M, Sester U, Kaul H, Kohler H. Molecular
aspects of T- and B-cell function in uremia. Kidney Int Suppl
2001;78:S206-11.
7. Papalois VE, Moss A, Gillingham KJ, Sutherland DE, Matas
AJ, Humar A. Pre-emptive transplants for patients with renal
failure: an argument against waiting until dialysis.
Transplantation 2000;70:625-31.
8. Meier-Kriesche HU, Port FK, Ojo AO et al. Effect of waiting
time on renal transplant outcome. Kidney Int 2000;58:1311-17.
9. Mange KC, Joffe MM, Feldman HI. Effect of the use or
nonuse of long-term dialysis on the subsequent survival of
renal transplants from living donors. N Engl J Med
2001;344:726-31.
10. Becker BN, Rush SH, Dykstra DM, Becker YT, Port FK.
Preemptive transplantation for patients with diabetes-related
kidney disease. Arch Intern Med 2006;166:44-8.
11. Butkus DE, Dottes AL, Meydrech EF, Barber WH. Effect of
poverty and other socioeconomic variables on renal allograft
survival. Transplantation 2001;72:261-6.
12. Shoskes DA, Cecka JM. Deleterious effects of delayed graft
function in cadaveric renal transplant recipients independent
of acute rejection. Transplantation 1998;66:1697-701.
13. Matas AJ, Gillingham KJ, Payne WD, Najarian JS. The
impact of an acute rejection episode on long-term renal
allograft survival (t1/2). Transplantation 1994;57:857-9.
14. Debska-Slizien A, Wolyniec W, Chamienia A et al. A single
center experience in preemptive kidney transplantation.
Transplant Proc 2006;38:49-52.
15. Abou Ayache R, Bridoux F, Pessione F et al. Preemptive renal
transplantation in adults. Transplant Proc 2005;37:2817-18.
16. Womer KL, Meier-Kriesche HU, Patton PR et al. Preemptive
retransplantation for BK virus nephropathy: successful
outcome despite active viremia. Am J Transplant 2006;6:209-
13.
17. Roubicek C, Brunet P, Huiart L et al. Timing of nephrology
referral: influence on mortality and morbidity. Am J Kidney
Dis 2000;36:35-41.
18. el-Agroudy AE, Donia AF, Bakr MA, Foda MA, Ghoneim
MA. Preemptive living-donor kidney transplantation: clinical
course and outcome. Transplantation 2004;77:1366-70.
19. Meier-Kriesche HU, Schold JD. The impact of pretransplant
dialysis on outcomes in renal transplantation. Semin Dial
2005;18:499-504.
20. Simforoosh N, Basiri A, Pourrezagholi F et al. Is preemptive
renal transplantation preferred? Transplant Proc
2003;35:2598-601.

Thank you for copying data from http://www.arastirmax.com