Journal Name:
- Indian Journal of Basic & Applied Medical Research
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Abstract (2. Language):
Introduction: Chronic kidney disease encompasses a spectrum of different pathophysiological
processes associated with progressive decline in glomerular filtration rate. Prevalence of CKD ranges
from 0.79% to 1.4%. Kidneys disease is ranked 3rd amongst life threatening diseases in India, after
cancer and heart disease. Anemia affects 60-80% of patients with renal impairment and common in
both pre-dialysis and on dialysis leading to decreased exercise tolerance, reduced quality of life and
additional risk factor for early death.
Materials and Methods: 50 cases of CKD were randomly selected for this cross sectional study
between October 2012 to August 2014. All patients were examined and investigated thoroughly as per
the proforma.
Results: The most common type of anemia was NNA with 33(66%) patients. MHA 9(18%) patients
and NHA 8(16%) patients mean Hb% was 8.49±1.17 gm%. Most common symptoms were facial
puffiness, 44(88%) patients easy fatiguability 39(78%) patients, pedal edema 36(72%), and decreased
urine output 21(42%) patients. Most common associated diseases were hypertension 43(86%),
diabetes mellitus 32(64%), ischaemic heart disease 14(28%) and dyslipidemia 7(14%). 40 patients
were on dialysis and 10 patients were on medical line treatment.
Conclusion: CKD is more prevalent in adult population with male predominance in older age
groups. Anaemia is the most common complication of CKD and severity of anemia increases
as CKD worsens and all patients had anemia. Both MHD and medical line treatment with
rEPO have beneficiary effects on Hb% levels.
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