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ANTI-VIRAL ACTIVITY OF AQUEOUS EXTRACT FROM BROWN SEAWEED, SARGASSUM ILLICIFOLIUM (TURNER) ON THREE DIFFERENT TYPES HERPES SIMPLEX VIRUS

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Abstract (2. Language): 
To evaluate the antiviral activity of aqueous extract of Brown Seaweed, Sargassum illicifolium on three types of herpes simplex viruses such as Wild type, Thymidine Kinase-Deficient and Acyclovir and Phosphonoacetic Acid Resistant ones. The anti-viral activity of aqueous extract of Sargassum illicifolium of different concentration such as 5%, 10%, 15%, 20%, 25% and controls both positive and negative were carried out against three types of Herpes Simplex Virus using Plaque Reduction Assay.The results indicated that in the negative control and lower concentrations (5%, 10%, 15%) there was no or least amount of antiviral activity which was followed by that of the positive control. Acyclovir, and the higher concentration of 20% and 25% showed better antiviral activity than that of the patented medicine. This preliminary study indicates that the aqueous extract of Sargassum illicifolium, is indeed endowed with antiviral properties against herpes simplex virus.
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