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Chromoblastomycosis- A report of a rare fungal infection from non endemic region of north India

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Abstract (2. Language): 
We report a case of 65 year old man who presented with complaints of itching and crusting over the knee. With a clinical impression of lichenoid dermatitis a skin biopsy was performed . The biopsy showed occasional ill defined granulomas and microabscesses. In view of the clinicopathologic discordance a careful scrutiny of the granulomas and microabscesses was carried out under oil immersion lens. Occasional penny shaped structures could be identified which were positive for fungal stains namely methenamine silver and Periodic Acid Schiff.(PAS). On literature search these were confirmed to be medlar bodies which are characteristic of a rare deep fungal infection namely chromoblastomycosis. The medlar bodies are often very few in histopathology specimens and are missed due to lack of awareness about this entity. The problem gets compounded when the clinical appearance suggests a different diagnosis.The case has been reported in view of its rarity and a brief review of chromoblastomycosis is presented.
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REFERENCES

References: 

1. López Martínez R, Méndez Tovar LJ. Chromoblastomycosis. Clin Dermatol. 2007 ;25(2):188-94. Review.
2 . Roy AD, Das D, Deka M. Chromoblastomycosis - A clinical mimic of squamous carcinoma. Australas Med J.
2013 30;6(9):458-60. .
3. Bandyopadhyay A, Majumdar K, Gangopadhyay M, Banerjee S. Cutaneous Chromoblastomycosis Mimicking
Tuberculosis Verrucosa Cutis: Look for Copper Pennies! Turk Patoloji Derg. 2013 . doi:
10.5146/tjpath.2013.01197.
4. Rosen T, Overholt M. Persistent viability of the Medlar body. Int J Dermatol. 1996 ;35(2):96-8.
5. Shanthala G.B., Rudresh S.M., Nagarathnamma T.. Chromoblastomycosis A case report. Journal of Clinical
and Diagnostic Research 2011 ; 5:865-866.
6. Fukushiro R. Chromomycosis in Japan. Int J Dermatol. 1983 ;22(4):221-9. Review.
7. Carrion AL . Chromoblastomycosis. Ann N Y Acad Sci. 1950 ;50(10):1255-82.
8. Diaz A, Pascal J, Monnin L, Bousquet C, Amat C, Michault A. Cerebral chromoblastomycosis. Apropos of a
case. Review of the literature. Neurochirurgie. 1996;42(2):95-9. Review. French.
9. Silva JP, de Souza W, Rozental S. Chromoblastomycosis: a retrospective study of 325 cases on Amazonic
Region (Brazil). Mycopathologia. 1998;143(3):171-5.
10. Sharma NL, Sharma RC, Grover PS, Gupta ML, Sharma AK, Mahajan VK. Chromoblastomycosis in India.
Int J Dermatol. 1999 ;38(11):846-51.
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Indian Journal of Basic and Applied Medical Research; March 2015: Vol.-4, Issue- 2, P. 72-75
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www.ijbamr.com P ISSN: 2250-284X , E ISSN : 2250-2858
11. Muhammed K, Nandakumar G, Asokan KK, Vimi P. Lymphangitic chromoblastomycosis. Indian J Dermatol
Venereol Leprol. 2006 ;72(6):443-5.
12. Esterre P, Peyrol S, Sainte-Marie D, Pradinaud R, Grimaud JA. Granulomatous reaction and tissue
remodelling in the cutaneous lesion of chromomycosis. Virchows Arch A Pathol Anat Histopathol.
1993;422(4):285-91.
13. d'Avila SC, Pagliari C, Duarte MI. The cell-mediated immune reaction in the cutaneous lesion of
chromoblastomycosis and their correlation with different clinical forms of the disease. Mycopathologia.
2003;156(2):51-60.
14. Queiroz-Telles F, Esterre P, Perez-Blanco M, Vitale RG, Salgado CG, Bonifaz A. Chromoblastomycosis: an
overview of clinical manifestations, diagnosis and treatment. Med Mycol. 2009;47(1):3-15.

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