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GLIOBLASTOMA' DA PROGNOZU ETKİLEYEN FAKTÖRLER

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Abstract (Original Language): 
Glioblastom (GB) genellikle beyinde yerleşmesine karşın, beyincik, beyin sapı ve omurilikte de yerleşebilir. GB'de birçok tedavi modellerinin kullanılmasına rağmen yaşam süreleri henüz arzulanan düzeylerde değildir. Prognoz; yaş, cins, öykü süresi, başlangç ve tedavi sonrası klinik tablo (Kamofsky Performans Skalası-KPS), tümör boyutu ve yerleşimi, cerrahi rezeksiyon oranı, brakiterapi, radyoterapi (RT) ve/veya kemoterapı uygulanması ve bu tedavilere yanıtı, histopatolo-jik olarakta nekroz, hemoraji ve tromboz varlığı gibi bulgulara bağlı olarak değişmektedir d.2,6). Beklenen yaşam süreleri agresif cerrahi ve ilave tedavilere karşın genellikle 1 yıldır, an¬cak 10 yıla kadar uzayan nadir yaşam süreleri bildirilmiştir (2,6,14,17),
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