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Hipotansiyon, Kronik Böbrek Yetmezlikli Hastada Mirtazapinin Etkisi

Hypotension, the Infl uence of Mirtazapine in a Patient with Chronic Renal Failure

Journal Name:

  • Türk Nefroloji, Diyaliz ve Transplantasyon Dergisi

Publication Year:

  • 2013
DOI: 
10.5262/tndt.2013.1003.13

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
In patients with end-stage renal disease (ESRD), depression is the most commonly identifi ed psychiatric illness; however, its prevalence varies since it is assessed by using different methods in different studies and in different populations. The commonly accepted view in the treatment of depression is a combination of psychotherapy and pharmacologic treatment. Mirtazapine is an antidepressant used in the treatment of major depressive illness which affects both noradrenergic and serotonergic activity. This paper is a case report of a 40 year old man with a history of renal failure who developed hypotension while receiving mirtazapine therapy. We believe that hypotension was a conclusion of the mirtazapine in our patient and hemodialysis had no infl uence on hypotension. Hypotension improved after the metabolization of mirtazapine (approximately thirty-six hours).
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Abstract (Original Language): 
Son dönem böbrek yetmezliği olan hastalarda depresyon en sık tanımlanan psikiyatrik hastalıktır, fakat depresyon prevalansı farklı çalışmalarda, farklı popülasyonlarda, farklı yöntemlerle değerlendirildiğinden değişiklikler göstermektedir. Depresyon tedavisinde kabul gören genel görüş tedavide psikoterapi ve ilaç tedavisinin kombinasyonu şeklindedir. Mirtazapin hem noradrenerjik hem de serotonerjik aktiviteyi etkileyen ve majör depresyon ile duygu durum hastalıklarında kullanılan anti depresan ilaçtır. Bu makalede, 40 yaşında böbrek yetmezliği öyküsü olan erkek hastada mirtazapin tedavisi sırasında gelişen hipotansiyon sunulmuştur. Düşüncemize göre, hipotansiyon mirtazapin kullanımın bir sonucu oluşmuştur ve hipotansiyon üzerine diyalizin bir etkisi yoktur. İlaç metabolize edildikten sonra hipotansiyon düzelmiştir (Yaklaşık 36. saat).
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  • Turkish

REFERENCES

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