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HERPES SİMPLEK S VİRÜS TİP 1 VE 2'YE BAĞLI GELİŞEN ERİTEMA MULTİFORME: OLGU SUNUMU

HERPES SIMPLEX VIRUS TYPE 1 AND 2 ASSOCIATED ERYTHEMA MULTIFORME: CASE REPORT

Journal Name:

  • İstanbul Üniversitesi Diş Hekimliği Fakültesi Dergisi

Publication Year:

  • 2006
Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
Erythema multiforme is an acute mucocutaneous hypersensitivity reaction, characterised by skin lesions, with or without involvement of the mucosa. Oral lesions are seen in 20 to 30% of the cases. Most common involvement is seen on the lips, buccal mucosa, tongue, soft palate and mouth floor. Skin manifestations are characterized by target or iris shaped lesions. Also macular, papular, vesicular, bullous, urticerized, plaque type skin lesions and hemoarragic and erosiv mucosal lesions are seen. Diagnosis is based on the clinical and histopathologic^! examination. This presentation evaluates the diagnosis arid succesfull treatment of the patient with antiviral drugs, who revealed erythema multiforme after a herpes simplex infection. Though Herpes Simplex Virus Type 1 and 2 are positive in microbiological examination; intraoral and extraoral lesions, symmetric skin lesions, genital lesions and accompanied by the positive mucosal biopsy confirmed the diagnose "erythema multiforme".
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Abstract (Original Language): 
Eritema multiforme, mukozal tutulum ile birlikte ya da olmaksızın deri lezyonlan ile karakterize, akut mukokütanöz aşın duyarlılık reaksiyonudur. Oral lezyonlar hastaların yaklaşık %20-30'unda görülür. En sık tutulum; dudak, bukkal mukoza, dil, yumuşak damak ve ağız tabanındadır. Deri lezyonlan iris şeklinde lezyonlar ile karakterizedir. Makûl, papül, vezikül, bül, ürtiker, plaklar ve hcmorajik, croziv mukoza lezyonlan da görülmektedir. Teşhis klinik ve histopatolojik görünümüne dayanır. Bu sunumda, herpes simpleks enfeksiyonunu takiben gelişen eritema multiforme olgusunun teşhisi ve sistemik antiviral ilaç kullanımı ile başanlı tedavisi sunulmaktadır. Mikrobiyolojik incelemede Herpes Simpleks Virüs Tip 1 ve 2'nin pozitif olarak bulunduğu olguda; intraoral ve perioral lezyonların yanı sıra simetrik cilt lezyonlan ve genital lezyonlar. ışığında ve histopatolojik inceleme neticesinde "eritema multiforme" ön tanısı doğrulanmıştır.
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  • Turkish

REFERENCES

References: 

İ. Geraminejad P,
Wallin
g HW, Voigt MD. Stone MS. Severe erythema multiforme responding to interferon alfa. J Am Acad Dermatol 2006; 54: S18-21.
2. Ghom AG. Textbook of oral medicine. Jaypee Brothers Medical Publishers Ltd. 2005; p; 667-671.
3. Gonzalez-Delgado P, Blanes M, Soriano V, Montoro D, Loeda C, Niverio E. Erythema multiforme to amoxicillin with concurrent infection by Epstein-Barr virus. Allergol Immunopathol (Madr) 2006; 34:76-78.
4. Jawetz, Melnick & Adelberg's Medical Microbiology. Brooks GF, Butel JS, Ornston LN, Jawetz E, Melnick JL, Adelberg EA. Appleton & Lange. 1991; p: 418-420.
5. Ayangco L, Sheridan PJ, Rogers RS. Erythema multiforme secondary to herpes simplex infection: a case report. J Periodontology 2001; 72: 953-957.
6. Farthing P, Bagan J-V, Scully C. Mucosal disease series. Number IV. Erythema multiforme. Oral Dis 2005; 11: 261-267.
7. Field A, Longman L, Tyldesley WR. Tyldesley's Oral Medicine.Oxford University Press. 5th edition. 2003; 135-136.
8. Malmstrom M, Ruokonen H, Konttinen YT, Bergroth V, Segerberg-Kottinen M, Hietanen J. Nordstrom D, Haapala M. Herpes simplex virus antigens and inflammatory cells in oral lesions in recurrent erythema multiforme. Immunoperoxidase and autoradiographic studies. Acta Derm Venerol 1990; 70 (5): 405-10.
9. Raborn GW, Grace MGA. Recurrent Herpes Simplex Labialis: Selected Therapeutic-Options. J Can Dent Assoc 2003; 69 (8): 498¬503
10. Wald A, Ericsson M, Krantz E, Selke S, Corey L. Oral shedding of herpes simplex virus type 2. Sex Transm Infect. 2004 Dec; 80 (6): 546.
11. Yura Y, Iga H, Kondo Y, Harada K, Yanagawa T, Yoshida H, Sato M. Herpes simplex virus and type 2 infection in human oral mucosa in culture. J Oral Pathol Med. 1991 Feb; 20 (2): 68-73.
12. Sun Y, Chan RK, Tan SH, Ng PP. Detection and genotyping of human herpes simplex viruses in cutaneous lesions of erythema
30
Kader CESUR AYDIN. Gökçen DURSUN. Şükrü ŞİRİN, Hakkı TANYERİ
multiforme by nested PCR. J Med Virol 2003; 71:423-8.
Bakis S, Zagarella S. Intermittent oral cyclosporin for recurrent herpes simplex-associated erythema multifotme. Australasian J Dermat 2005 Feb; 46: 18.
Aurelian L, Ono F, and Burnett J. Herpes simplex virus (HSV)-associated erythema
multiforme (HAEM): A viral disease with an autoimmune component. Dermatol Online J. 2003 Feb; 9 (1): I.
15. Gonzalez-Delgado P, Blanes M, Soriano V, Montoro D, Loeda C, Niverio E. Erythema multiforme to amoxicillin with concurrent infection by Epstein-Barr virus. Allergol Immunopathol (Madr) 2006; 34: 76-78.

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