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DıŞ HEKIMLIĞINDE HYALURONIK ASIDIN YERI

HYALURONIC ACID IN DENTISTRY

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Abstract (2. Language): 
Hyaluronic acid (HA), which is one of the primary components of the extracellular matrix, is synthesized by fibroblasts and chondrocytes. Hyaluronic acid is a polysaccharide that takes place at cell proliferation, tissue regeneration, cell migration and progression of some malignant tumors. Hyaluronic acid has been widely used in ophthalmology, rheumatology, orthopedic and dermatology because of its anti-inflammatory and anti-edematous effects. Hyaluronic acid is recently used in dentistry for treatment of temporomandibular joint osteoarthritis, ulcerative lesions and oral surgery. In this essay, our aim is to lay out the actual information about the utilization of HA that is commonly used in various areas, in dentistry.
Abstract (Original Language): 
Hyaluronik asit (HA), ekstrasellüler matriksin ana komponentlerinden biri olup fibroblastlar ve kondrositler tarafından sentezlenir. Hücre proliferasyonunda, doku tamirinde, hücre göçünde ve bazı malign tümörlerin progresyonunda rol oynayan bir polisakkarittir. Günümüzde HA tıp alanında anti-inflamatuar ve anti-ödematöz özelliklerinden dolayı oftalmoloji, dermatoloji, ortopedi ve romatoloji dallarında sıklıkla kullanılmaktadır. Diş hekimliğinde kullanımı çok yeni olmakla beraber temporomandibular eklem (TME) osteoartrit tedavisinde, ülseratif lezyonların tedavisinde ve cerrahi operasyonlarda kullanılmaktadır. Bu derlemede, bizim amacımız birçok alanda kullanılan HA'nın diş hekimliğinde kullanımı ile ilgili güncel bilgileri aktarmaktır.
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