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İkinci Basamak Devlet Hastanesi Nefroloji Kliniği Periton Diyaliz Hastalarının Klinik Sonuçları

Clinical Outcomes of Peritoneal Dialysis Patients at a Secondary State Hospital Nephrology Clinic

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DOI: 
DOI 10.5262/tndt.2012.1001.06

Keywords (Original Language):

Abstract (2. Language): 
OBJECTIVE: We present our experience with demographics, clinical and biochemical outcomes, and factors affecting mortality in ESRD patients treated with peritoneal dialysis (PD) during a 12-year period (1997–2009) at secondary state hospital’s nephrology clinic. MATE RIAL and methods: After excluding patients younger than age 15 at the initiation of PD, those who had follow-ups at less than three months, outcomes were analyzed for 313 patients. The demographic, clinical, and biochemical data were collected from the patients’ medical records. Res ults: The mean age at the start of PD was 51.9 ± 17.6 years and the mean PD duration was 27.5 ± 27.1 months (median: 20, range: 3–166). Hypertension was the most common cause of ESRD (36.1%), followed by diabetes mellitus (31.3%). Among these 313 patients, 58 (18.5%) died. Patients’ survival rates were 93.3%, 85%, and 72.4%, at one, three, and five years, respectively. A higher educational level (p=0.045), lower age (p=0.002), higher baseline creatinine (p=0.045), and higher baseline albumin level (p=0.003) were found to affect patients’ survival. Technique survival rates were 89.1%, 84%, and 74.1% at one, three and five years, respectively. Technique failure was associated with peritonitis rate (p=0.03). ConclusI on: Our results suggest that patients’ and technique survival rates and the factors affecting mortality in our patients at a secondary state hospital’s nephrology clinic were similar to those at a tertiary care university hospital’s nephrology clinic in Turkey.
Abstract (Original Language): 
Amaç : İkinci basamak tedavi kurumu olarak kliniğimizde 12 yıl boyunca (1997–2009) periton diyaliz tedavisi uygulanan son dönem böbrek yetmezlikli hastaların demografik, klinik ve biyokimyasal özellikleri ve mortaliteyi etkileyen faktörlerini sunmaktayız. GEREÇ ve YÖNTEMLER: Periton diyalizine başlama yaşı 15’in altında olan ve üç aydan daha kısa süre izlenen hastaların çıkarılmasından sonra toplam 313 hastanın sonuçları değerlendirildi. Hastaların demografik, klinik ve biyokimyasal özellikleri tıbbi hasta dosyalarından kaydedildi. Sonuç: Ortalama periton diyalizine başlama yaşı 51,9 ± 17.6, periton diyaliz süresi 27,5 ± 27,1 ay idi (ortanca: 20, aralık: 3–166). Son dönem böbrek yetmezliğinin en sık nedeni hipertansiyon (%36,1) ve bunu izleyen diyabetes mellitus (%31,3) idi. 313 hastanın 58’i öldü (%18,5). Hasta sağ kalım oranı birinci, üçüncü ve beşinci yılda sırayla %93,3, %85 ve %72,4 olarak bulundu. Yüksek eğitim düzeyi (p=0,045), genç yaş (p=0,002), yüksek bazal kreatinin düzeyi (p=0,045), ve yüksek bazal serum albumin düzeyi (p=0,003) hasta sağ kalımını etkileyen faktörler olarak saptandı. Teknik sağ kalım oranları birinci, üçüncü ve beşinci yılda sırayla %89,1, %84 ve %74,1 olarak bulundu. Teknik yetersizlik peritonit hızıyla ilişkili saptandı (p=0.03). Tar tışma : Bizim sonuçlarımız ikinci basamak sağlık kuruluşu nefroloji kliniği olarak hasta ve teknik sağkalım oranları ve hasta mortalitesini etkileyen faktörlerin Türkiye’deki üçüncü basamak üniversite hastanelerinin sonuçlarına benzediğini göstermektedir.
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