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CANDİDA’LARIN PATOJENLİK BELİRTGENLERİ

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Abstract (2. Language): 
A number of factors mainly related to fungus species and strains have contributed to overcome the host defences. The so called pathogenicity determinants confer virulence on Candida albicans and other Candida species. These factors are adherence (adhesion to mucosal surfaces), dimorphism (production of hyphae and resistance to phagocytosis), toxin and enzyme production and cell surface composition.
Abstract (Original Language): 
Esasen mantarın türüne ve kökene bağlı olan bir kısım faktörler konağın bağışıklığını yenmek için birlikte rol oynarlar. Patojenlik belirtgenleri denilen bu faktörler C. albicans ve diğer Candida türlerinin virülensini belirlerler. Candida ’larda bu faktörler başlıca adherens (mukoza epitel hücrelerine yapõşma), dimorfizm (hif üreterek fagositoza direnç gösterme), toksin (yüksek ve düşük molek ül ağırlıklı) ve enzim (proteinazlar; fosfolipazlar ve lizofosfolipazlar) üretimi ve hücre yüzeyinin kompozisyonu olarak gruplandırılabilir.
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