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SUSTAINED RELEASE SOLID DOASGE FORM: CONCEPT AND FORMULATION DESIGN NECCESITIES

Journal Name:

  • The International Journal of Pharmaceutical Research and Bio-Science

Publication Year:

  • 2013

Key Words:

Author Name
Abstract (2. Language): 
Oral Sustained release (SR) products provide an advantage over conventional dosage forms by optimizing bio pharmaceutics, pharmacokinetic and pharmacodynamic properties of drugs in such a way that it reduces dosing frequency to an extent that once daily do therapeutic management through uniform plasma concentration providing maximum utility of drug with reduction in local and systemic side effects and cure or control condition in shortest possible time by smallest quantity of drug to assure greater patient compliance. Developing oral sustained release matrix tablets for drugs with constant release rate has always been a challenge to the pharmaceutical technologist. Drug release through matrix system is determined by water penetration, pol dissolution, drug diffusion and matrix erosion. Highly water soluble drugs like Diltiazem; Ranitidine has been formulated as sustained release matrix tablets. This article contains the basic information regarding design sustained and also the different types of the same
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  • 1
104-123
  • English

REFERENCES

References: 

1. Brannon PL: L. Med. Plast. & Biomater,
Med. Plast. & Biomater; 1998; 199(6): 34-
46.
2. K.P. Sampath kumar, Debjit Bhowmik,
Shweta Srivastava, Shravan Paswan and A.S.
Dutta: Sustained Release Drug Delivery
System Potential, The Pharma Innovation.,
2012; 1(2): 48-60.
3. Chien YW: Novel drug delivery systems.
2nd ed. New York: Marcel Dekker Inc; 1992.
4. Lachman L, Lieberman HA and Kanig JL:
The theory and practice of industrial
pharmacy. 3 rd ed. Bombay: Varghese
Publishing House; 1987.
5. Remington: the Science and practice of
pharmacy; Lippincott Williams & wilkins
20th edition; 2002; 903-914.
6. Gwen M Jantzen; Joseph R Robinson;
Sustained, controlled and targeted Drug
Delivery; Marcel dekker, 2nd edition; 1989;
29-32.
7. Gudsoorkar VR, Rambhau D. sustained
release of drugs. The Eastern Pharmacist
1993; 36 (429): 17-22.
8. D. M. Brahmankar & Sunil B. Jaishwal,
Controlled release medication chapter 15th
in Biopharmaceutics and Pharmacokinetics
– A Treatise, 1st edition, Vallabh Prakashan:
347-353.
9. Rane Manish, Parmar Jayesh,
Siahboomi Ali Rajabi. Hydrophilic Matrices
for Oral Extended Release Influence of
Fillers on Drug Release from HPMC
Matrices. Pharma Times. 2010; 42(4).
10. Baker R W and Heller J: Material
selection for trans-dermal delivery systems;
In Had graft J, Guys R H, editors.
Transdermal Drug Delivery: Development
Issues and Research Initiatives. New York,
Marcel DekkerInc.1989; 293-311.
11. Bromberg L: Crosslinked poly ethylene
glycol networks as reservoirs for protein
delivery, J Apply Poly Sci1996; 59; 459-466.

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