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DEVELOPMENT AND EVALUATION OF CEFPODOXIME PROXETIL GELLAN GUM BASED IN SITU GEL

Journal Name:

  • The International Journal of Pharmaceutical Research and Bio-Science

Publication Year:

  • 2012

Key Words:

Author Name
Abstract (2. Language): 
Among oral dosage form, liquid dosage forms are more prone to low bioavailability because of their quick transit from the gastrointestinal tract. Sustained release liquid formulation with efficacy can be produced using approach of In situ gel. The purpose of the present work was to develop oral in situ gelling system using Gellan gum for in situ gelation of Cefpodoxime proxetill. Optimized formulations were prepared having desirability and evaluated for various parameter. The developed formulation was stable, non-irritant and provided sustained release over 8-hour period and it is a viable alternative to conventional dosage form.
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  • English

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