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HEMODİALİZ HASTALARINDA TRANSFUSION TRANSMITTED VIRUS INFEKSIYONU, HCV ve HGV ILE BIRLIKTELIĞI

CONSIDENCE OF TTV, HCV AND HGV ENFECTIONS IN HEMODIALYSIS PATIENTS

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Abstract (2. Language): 
We aim to study infection of Transfusion Transmitted virus and associated with HGV and HCV on hemodialysis patients with chronic renal failure. This study was performed on 50 hemodialysis patients (30 male, 20 female) that are on routine hemodialysis program in Uludağ University Hemodialysis Centre and 100 healthy blood donors as the control group (45 female, 55 male). The average ages of patients and healthy groups were 39+14 and 34+9.2 respectively. In healthy blood donor group TTV was only studied and TTV positivity was found to be 12%. TTV positivity of patients was 36% and associated with HCV and HGV were 25.4 % and 27.9 % respectively. As a result, TTV positivity in hemodialysis patients was statistical)' significant when compaired with healthy blood donors(P<0.05). Association of TTV with HGV and HCV was not found to be statistical}' significant.
Abstract (Original Language): 
Bu çalışma kronik böbrek yetmezlikti hemodializ hastalarında Transfusion Transmitted virus enfeksiyonu, HGVve HCV ile birlikteliğini araştırmayı amaçladık. Çalışma Uludağ Üniversitesi Hemodializ Ünitesinde kronik hemodializ programında olan 50 hasta (30 'u erkek, 20 'si kadın) ile kontrol grubu olarak 100 sağlıklı kan donörÜ (45i kadın, 55i erkek) üzerinde yapıldı. Hasta grubunun yaş ortalaması 39±14, ortalama dializ süresi 7.0+3.9 (5ay-17yıl) yıl idi. Sağlıklı kan donörlerin yaş ortalaması 34+9.2 yıldı. Bu grupta sadece TTV bakıldı. Pozitiflik oranı %12, hasta grubunda ise %36 olarak saptandı. TTV; anti-HCV ile birlikteliği %o20.4, HGV ile birlikteliği %o27.9 olarak tespit edildi. Sonuç olarak kronik hemodializ hastalarında TTV, sağlıklı kan donörlere göre istatistiksel olarak anlamlı düzeyde yüksek tespit edildi (P<0.05). TTV; HGV ve HCV ile birlikteliği istatistiksel olarak anlamlı değildi (P>0.05).
FULL TEXT (PDF): 
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REFERENCES

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